Open data · MSFrontier

CSV files, one per table, with a data dictionary. Updated every Sunday.

File	Contents	Download
trials.csv	One row per trial after duplicates across registries are merged.
registry_ids.csv	Every registry number known for each trial.
findings.csv	What each trial found, by the same rules as the trial pages, with the source of each finding.
primary_analyses.csv	Statistical analyses of main outcomes posted on ClinicalTrials.gov.
hypotheses.csv	Every hypothesis with its status and the rules version that set it.
hypothesis_evidence.csv	Which trials bear on which hypothesis, and whether each counts toward its status.
medicines.csv	Medicines approved for MS, NMOSD and MOGAD, with approvals and trial counts.
results_watch.csv	Finished trials and whether their results could be found.
trial_links.csv	Links between trials stated in the registries, such as extensions.
lab_studies.csv	Original animal and human cell studies since 2015, with models, interventions and findings.Not included in the latest release yet.
lab_links.csv	Links from lab studies to approaches, hypotheses, treatments, genes and frontiers.Not included in the latest release yet.
lab_interventions.csv	Interventions studied in the lab, their findings and links to trials in people.Not included in the latest release yet.
lab_genes.csv	Genes targeted in lab studies, with human genetics and medicines in trials.Not included in the latest release yet.
README.md	The data dictionary: what each column means.

Licence and how to cite

MSFrontier's own work in these files (merged records, tags, mechanism groups, findings, hypotheses and their statuses, and the results watch) is released under the Creative Commons Attribution 4.0 licence (CC BY 4.0). Please cite: MSFrontier Trial Bank, 2026-11-02, https://screenshot-to-pixel-perfect-519.lovable.app.

Registry content such as titles, dates and sponsors comes from ClinicalTrials.gov, the EU Clinical Trials Register, CTIS and ISRCTN and remains subject to each registry's terms. Medicine identifiers come from ChEMBL (CC BY-SA 3.0). Quoted sentences come from published abstracts.

For developers

The code that builds the data is open on GitHub .

Assembled by software from public sources and not checked by people. Each record links to its source. Report an error