A course on how multiple sclerosis works, how it is diagnosed and measured, what causes it and how its treatments work. It is written at the depth of a clinical training course, with every technical term explained in the margin, and each lesson ends with what research is doing on its topic now.

Start module 1

12 modules · 36 lessons · about 2.3 hours

Module 1

Nerves and myelin

0 of 2 lessons read

  1. 1.What is multiple sclerosis?
  2. 2.Myelin, axons and the cells that make them

Module 2

The immune system in MS

0 of 2 lessons read

  1. 1.What happens in the body
  2. 2.T cells, B cells and the blood-brain barrier

Module 3

Lesions and pathology

0 of 2 lessons read

  1. 1.How a lesion forms and evolves
  2. 2.Smouldering inflammation and the cortex

Module 4

Attacks and progression

0 of 2 lessons read

  1. 1.Types, courses and the spectrum
  2. 2.Relapses, PIRA and NEDA

Module 5

Diagnosis

0 of 3 lessons read

  1. 1.Symptoms
  2. 2.How MS is diagnosed
  3. 3.Spinal fluid, oligoclonal bands and kappa free light chains

Module 6

Imaging in depth

0 of 2 lessons read

  1. 1.How MRI shows MS
  2. 2.Rims, central veins and atrophy

Module 7

Biomarkers and measures

0 of 3 lessons read

  1. 1.How MS is measured
  2. 2.Neurofilament light and GFAP
  3. 3.OCT and evoked potentials

Module 8

Causes and genetics

0 of 3 lessons read

  1. 1.Causes and risk factors
  2. 2.Epstein-Barr virus in depth
  3. 3.Genetics of susceptibility and severity

Module 9

Who gets MS

0 of 1 lessons read

  1. 1.Who gets MS

Module 10

Conditions that resemble MS

0 of 3 lessons read

  1. 1.Conditions that resemble MS
  2. 2.Medicines for NMOSD and MOGAD
  3. 3.MS and neurodegenerative diseases

Module 11

How treatments work

0 of 11 lessons read

  1. 1.What a treatment has to do
  2. 2.Biologics and small molecules
  3. 3.From an idea to an approved medicine
  4. 4.The first medicines: interferon beta and glatiramer acetate
  5. 5.Keeping immune cells out of the brain
  6. 6.Removing B cells
  7. 7.Calming and slowing immune cells
  8. 8.Resetting the immune system
  9. 9.Reaching inflammation inside the brain
  10. 10.Treating relapses and symptoms
  11. 11.What the medicines have taught us

Module 12

History and where we stand

0 of 2 lessons read

  1. 1.A history of MS
  2. 2.Where understanding stands

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