MSFrontier · updated every week
A map of multiple sclerosis research
MSFrontier brings together research on multiple sclerosis from many sources: the clinical trials registered around the world, their results, the reviews that pool them, and news from regulators and journals. From this we keep an account of what is known about MS, what is still uncertain, and which ideas are being tested now.
It is written for people with MS and those close to them, for clinicians and for researchers. Most of it is assembled by software from public sources, and every figure links to the record it comes from.
What is on the site
Research
Eight questions that organise MS research, from what starts the disease to whether damage can be repaired. Each has a short account of the evidence, the ideas being tested and the trials to watch.
The eight questions →
Data
The trial database, the ideas the trials test, approved and experimental medicines, and reviews and result papers. Everything can be searched, filtered and downloaded.
Data overview →
Learn
A course on how MS works, how it is diagnosed and measured, and how treatments work. It is written for readers with and without medical training, and explains each technical term.
MS in depth →
News
Trial results, regulatory decisions and new papers each week, and a calendar of results expected in the coming months.
This week's news →Where the evidence stands
For each research question, the ideas being tracked and what the trials have shown so far. Choose a type of MS to narrow it down.
What starts MS
Stopping inflammation
Why MS progresses
Repair and protection
Symptoms and everyday function
Resetting the immune system
Measuring MS
Related diseases: NMOSD and MOGAD
Being tested now
Trials to watch
Running trials whose results could change what is known, chosen every week by fixed rules.
Progressive MS
Loading trials to watch…
Repair and protection
Loading trials to watch…
Towards lasting remission
Loading trials to watch…
Who it is for
People with MS and their families
Find out what is being tested for your type of MS, what has already been tried, and when results are expected. The Learn course explains the background.
Clinicians
Trial results, outcome measures and the evidence for each approach in one place, with the original sources for every statement.
Researchers
A database of trials, results and hypotheses that can be filtered and downloaded, including the trials whose results could not be found.
How it is put together
Sources. Trial registries in the US, the EU and the UK, the European and US regulators, and Europe PMC for papers. Every record links to its source.
Rules. Software tags each trial, reads results and judges each idea by fixed rules that are published on the site. The same rules apply to every medicine.
Review. The data are not checked one by one by people, and the course has not yet been reviewed by an MS specialist. We say so on every page.
Corrections. When an error is reported, we fix the rule rather than the single record, and list the change in the corrections log.
This week
No updates currently available.
All news →