Failed early

primary progressive MS · T-cell co-stimulation / cytokine targeting

Controlled phase 2 trials were negative.

Laquinimod was refused in the EU. A positive trial result does not mean the medicine is available.

Trials
1
Running now
0
Controlled phase 2/3 trials
1
People in controlled trials
374

Deciding trials (phase 2): 0 met, 1 did not.

Other linked trials: 0

Dose comparisons, trials against another medicine, add-on trials, phase 1 and uncontrolled studies. They are listed below but do not set the status.

Trials

  • ARPEGGIOdecides the statusMissed main goal

    Phase 2 · 2015 · Placebo-controlled · MSFT-NCT02284568

The deciding phase and counts come from the Trial Bank’s fixed rules.

Lab evidence

Lab studies in animals or cells. Results in animals often do not hold in people, and these studies never change the status of an idea.

Loading lab studies…

Loading reviews and guidelines…

History

  • 2026-10-27First listed as Failed early

Related hypotheses

Assembled by software from public sources and not checked by people. Each record links to its source. Report an error