MSFrontier

Being tested

Immune reconstitution (cladribine, alemtuzumab, aHSCT): reset the immune system for lasting remission in relapsing MS

Trial timeline

Phase 320052007

Trial start year. Dot size reflects participants where reported. Only trials that count towards the status are shown.

relapsing MS · Immune reconstitution (cladribine, alemtuzumab, aHSCT)

Trials are running now and no controlled trial has a readable result yet.

Trials
23
Running now
1
Controlled phase 2/3 trials
5
People in controlled trials
4371

Deciding trials (phase 3): 3 met, 0 did not.

Other linked trials: 20

Dose comparisons, trials against another medicine, add-on trials, phase 1 and uncontrolled studies. They are listed below but do not set the status.

Trials

  • CARE-MS IIdecides the statusMet main goal

    Phase 3 · 2007 · Compared with interferon beta-1a · MSFT-NCT00548405

  • CARE-MS Idecides the statusMet main goal

    Phase 3 · 2007 · Compared with interferon beta-1a · MSFT-NCT00530348

  • Oral Cladribine versus Placebo in RRMSdecides the statusResult in a paper, not read yet

    Phase 3 · 2005 · Placebo-controlled · MSFT-2004-005148-28

  • CLARITYdecides the statusMet main goal

    Phase 3 · 2005 · Placebo-controlled · MSFT-NCT00213135

Other linked trials: 20

These linked trials do not set the status.

The deciding phase and counts come from the Trial Bank’s fixed rules.

Lab evidence

Lab studies in animals or cells. Results in animals often do not hold in people, and these studies never change the status of an idea.

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History

  • 2026-10-27First listed as Being tested

Related hypotheses

Assembled by software from public sources and not checked by people. Each record links to its source. Report an error