Mixed
Arbaclofen: improve symptoms or function in MS (type not specified)
MS (type not specified) · Spasticity
Controlled trials disagree.
- Trials
- 2
- Running now
- 1
- Controlled phase 2/3 trials
- 2
- People in controlled trials
- 978
Deciding trials (phase 3): 0 met, 0 did not.
Other linked trials: 1
Dose comparisons, trials against another medicine, add-on trials, phase 1 and uncontrolled studies. They are listed below but do not set the status.
Trials
- A Study to Investigate Arbaclofen ER Tablets for the Treatment of Spasticity in Patients With Multiple Sclerosisdecides the statusOngoing
Phase 3 · 2027 · Placebo-controlled · MSFT-NCT05179577
Phase 3 · 2018 · Placebo-controlled · MSFT-NCT03290131
Improvements were seen in the mean Clinical Global Impression of Change scores for both the arbaclofen extended-release 40 mg/day and placebo groups; however, no statistically significant difference was observed between them (least squares mean difference: -0.10; P = 0.43).
Read by software from the paper's abstract
The deciding phase and counts come from the Trial Bank’s fixed rules.
Lab evidence
Lab studies in animals or cells. Results in animals often do not hold in people, and these studies never change the status of an idea.
Loading lab studies…
Loading reviews and guidelines…
History
- 2026-10-28First listed as Mixed
Related hypotheses
- Spasticity: improve symptoms or function in MS (type not specified)
- Arbaclofen: improve symptoms or function in relapsing and progressive MS
- Baclofen: improve symptoms or function in MS (type not specified)
- Botulinum toxin type a: improve symptoms or function in MS (type not specified)
- Cannabidiol: improve symptoms or function in MS (type not specified)
- Dronabinol: improve symptoms or function in MS (type not specified)
- Nabilone: improve symptoms or function in MS (type not specified)
- Nabiximols: improve symptoms or function in MS (type not specified)
- Onabotulinumtoxina: improve symptoms or function in MS (type not specified)
- Rimabotulinumtoxinb: improve symptoms or function in MS (type not specified)
- Tizanidine: improve symptoms or function in MS (type not specified)
Assembled by software from public sources and not checked by people. Each record links to its source. Report an error