Confirmed
Two or more controlled phase 3 trials met their main goal.
Laquinimod: reduce relapses and new lesions in relapsing MS
Trial timeline
Trial start year. Dot size reflects participants where reported. Only trials that count towards the status are shown.
relapsing MS · T-cell co-stimulation / cytokine targeting
Two or more controlled phase 3 trials met their main goal, or one did and a medicine of this approach is approved for this use.
Laquinimod was refused in the EU. A positive trial result does not mean the medicine is available.
- Trials
- 5
- Running now
- 0
- Controlled phase 2/3 trials
- 4
- People in controlled trials
- 4162
Deciding trials (phase 3): 2 met, 0 did not.
Other linked trials: 3
Dose comparisons, trials against another medicine, add-on trials, phase 1 and uncontrolled studies. They are listed below but do not set the status.
Trials
Phase 3 · 2008 · Compared with interferon beta-1a · MSFT-NCT00605215
Phase 3 · 2007 · Placebo-controlled · MSFT-NCT00509145
Phase 3 · 2007 · Placebo-controlled · MSFT-2007-003226-19
Other linked trials: 3
These linked trials do not set the status.
- LIBRETTOStopped, other reason
Phase 3 · 2014 · Compared with interferon beta-1a
- A Study to Evaluate the Effectiveness, Tolerability and Safety of LaquinimodResult in a paper, not read yet
Phase 2 · 2005 · Placebo-controlled
The deciding phase and counts come from the Trial Bank’s fixed rules.
Lab evidence
Lab studies in animals or cells. Results in animals often do not hold in people, and these studies never change the status of an idea.
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History
- 2026-10-27First listed as Confirmed
Related hypotheses
- Abatacept: reduce relapses and new lesions in relapsing MS
- Daclizumab: reduce relapses and new lesions in relapsing MS
- Dapirolizumab pegol: reduce relapses and new lesions in relapsing MS
- Frexalimab: reduce relapses and new lesions in relapsing MS
- Secukinumab: reduce relapses and new lesions in relapsing MS
- Ustekinumab: reduce relapses and new lesions in relapsing MS
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