Systematic reviews, meta-analyses and clinical guidelines on MS, NMOSD and MOGAD since 2015. Reviews pool the results of many studies, so they are often the best single summary of what is known. Each one is tagged by software and linked to the medicines, hypotheses and frontiers it covers.
1021Meta-analysis
734Systematic review
24Umbrella review
47Guideline
134Consensus statement
Treatment reviews441Found a benefit
39No benefit found
104Mixed
20Found harm
117Evidence too weak to say
Meta-analysis · 2026 · Journal of neurovirology · 131 studies
Researchers pooled published studies from Middle East and North Africa and found MS cases and EBV infections both rose over time, with MS rising more sharply.
From the abstract
Based on a probable ecological correlation between the increasing prevalence of MS and EBV, the preventive measures against EBV infection may potentially yield favorable outcomes in terms of MS prevention.
MS in general
Tagged by software from the title and abstract. The quote is copied word for word.
Systematic review · 2024 · Multiple sclerosis and related disorders · 36 studies
A review of 36 studies found EBV antibody levels do not reliably predict MS course, though they may reflect disease activity and treatment response.
From the abstract
EBV antibody levels are unlikely to represent prognostic biomarkers in MS.
MS in general
Tagged by software from the title and abstract. The quote is copied word for word.
Meta-analysis · 2023 · Microbial pathogenesis
Researchers pooled 134 studies and found that infection with EBV, VZV and herpesvirus 6 is linked to a higher chance of developing multiple sclerosis.
From the abstract
The results of the present study showed that EBV, VZV, and HHV-6 infection are associated with multiple sclerosis and can be considered as potential risk factors for MS.
MS in general
Tagged by software from the title and abstract. The quote is copied word for word.
Systematic review · 2021 · Current journal of neurology · 16 studies
This review of 16 studies from the Middle East and North Africa found that sunlight may protect against MS, while smoking, measles, EBV infection and stress may raise risk.
From the abstract
Among 47 assessed risk factors, sunlight exposure, cigarette smoking, measles infection, Epstein-Barr virus (EBV) infection, and stressful events had a significant association with MS.
MS in general
Tagged by software from the title and abstract. The quote is copied word for word.
Umbrella review · 2015 · The Lancet. Neurology · 416 studies
Researchers reviewed 44 meta-analyses of environmental factors and MS. Only EBV antibodies, infectious mononucleosis, and smoking showed strong, reliable links to developing the disease.
From the abstract
A biomarker of Epstein-Barr virus (anti-EBNA IgG seropositivity), infectious mononucleosis, and smoking showed the strongest consistent evidence of an association.
MS in general
Tagged by software from the title and abstract. The quote is copied word for word.