Interferon beta-1b
How it works: The first medicines: interferon beta and glatiramer acetate →
Betaferon
EU: Approved in the EU since 1995US: FDA approved 1993
- Molecule type
- Protein
- Mechanism (ChEMBL)
- Interferon alpha/beta receptor agonist
- Targets
- Interferon alpha/beta receptor
- Availability
- Authorised in all EU and EEA countries. Reimbursement is decided by each country.
Approvals
Other regulatory events
- Withdrawn · Extavia2025-04-25 Source
Safety communications
None recorded.
Most-reported side effects (FDA reports)
Reports to the FDA's adverse event system (FAERS) show what people and doctors reported while taking the medicine. They do not prove the medicine caused it, and they are not rates.
19,777 reports in total, 11,313 marked serious.
- Influenza like illness1,427
- Multiple sclerosis relapse1,420
- Fatigue1,232
- Injection site pain1,217
- Multiple sclerosis1,203
- Drug ineffective996
- Injection site erythema993
- Pain884
- Headache880
- Injection site reaction852
Trials
Key trials
Large trials with a reported result on their main goal.
- Interferon beta-1b, phase 3
Completed · Phase 3 · Relapsing and progressive · Main goal met
- Interferon beta-1b, phase 3
Completed · Phase 3 · Relapsing MS · Main goal not met
- Interferon beta-1b, phase 3
Completed · Phase 3 · Early (CIS/RIS) · Main goal met
Running now
- TWINS
Not yet recruiting · Phase 3 · Relapsing MS · ongoing
- INFORM
Running, not recruiting · MS (type not specified) · ongoing
- STOP-I-SEP
Running, not recruiting · Phase 3 · Progressive MS · ongoing
- DELIVER-MS
Running, not recruiting · Phase 4 · Relapsing MS · ongoing
- ABIRISK
Ongoing · Phase 4 · MS (type not specified) · ongoing
- VITAD-2010
Ongoing · Phase 2 · Relapsing and progressive · ongoing
Other trials (56)
Completed small trials, dose-finding studies and trials in other diseases.
- Interferon beta-1b
Completed · MS (type not specified) · no_result_found
- Interferon beta-1b
Completed · MS (type not specified) · no_result_found
- PERFECT
Completed · Relapsing MS · no_result_found
- Interferon beta-1b
Completed · Relapsing and progressive · result_in_paper_unread
- PLENO
Completed · Phase 4 · Relapsing MS · no_result_found
- Interferon beta-1a
Completed · MS (type not specified) · no_result_found
- Interferon beta-1b
Completed · Relapsing MS · no_result_found
- Interferon beta-1b
Completed · Relapsing MS · result_in_paper_unread
- Interferon beta-1b, phase 1
Completed · Phase 1 · MS (type not specified) · no_result_found
- Interferon beta-1b
Completed · Relapsing MS · no_result_found
For information only, not medical advice. Talk to your neurologist before changing treatment.
Hypotheses involving this medicine
Loading hypotheses…
Loading reviews and guidelines…
Lab studies
Lab studies in animals or cells. Results in animals often do not hold in people, and these studies never change the status of an idea.
Loading lab studies…
Assembled by software from public sources and not checked by people. Each record links to its source. Report an error