Stopped earlyPhase 2Relapsing MS2018-000620-34

What was tested

Treatment tested

  • Imatinib

Compared with

  • Methylprednisolone

    Glucocorticoid receptor agonist

What it measured

Main measures

  • 1. The primary endpoint is mean change between baseline and day 28 in the most worsened FSS due to the acute relapse comparing MP and Imatinib. In case more than one domain is affected, priority of selected FSS should be in the following order: 1) Pyramidal, 2) Brain stem, 3) Cerebellar, 4) Visual, 5) Sensory. At least a two step deterioration due to neuroinflammatory bout should have occurred. Bo

    RelapsesFatigueBladder, bowel and sexual function

Other measures (1)

  • 1.Mean change between baseline and week 12 in the most worsened FSS due to the acute relapse

    RelapsesFatigue

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Related trials

History

  1. In scope changed from true to false
  1. Started

    Mar 2018

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