Not yet recruitingPhase 2Progressive MS2026-525817-29-00

What it found

Still running

No result yet.

What was tested

Treatment tested

  • SUN-627

What it measured

Main measures

  • Incidence of treatment-emergent adverse events (TEAEs) and serious adverse events (SAEs) Time Frame: From enrollment to the end of study at 16 weeks

    Safety

Other measures (1)

  • Markers of disease in blood and brain fluid as well as imaging to measure inflammation Time Frame: from enrollment to the end of treatment at 12 weeks

Who could take part

Progressive MS · 18 and over

Inclusion: - Aged 18-70, inclusive - Diagnosis of PPMS or non-active SPMS - No MS relapses in the past 2 years - Evidence that MS has continued to get worse over time - A level of disability that fits the study requirements - Additional inclusion criteria are outlined in the full study protocol. Exclusion: - Use of certain medications or treatments before the study, or need for these treatments during the study - Current participation in another research study - Certain abnormal heart rhythm findings on ECG or other heart conditions that may increase risk - Certain serious or unstable medical conditions that could make the study unsafe - Active infection, recent infection, or a history of repeated infections - Additional exclusion criteria are outlined in the full study protocol.

As registered. Criteria can change, so ask the trial team or your neurologist.

Contact details on the registry

About this trial

In the sponsor's words

To assess safety and tolerability of SUN-627

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History

    1. Started

      Oct 2026

    2. Finished

      Apr 2027

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