The Effects of Ethyl-Alpha-Guanido-Methyl Ethanoate on Skin Reactions From Glatiramer Acetate Injections
What it found
The trial ended early for another reason (see below).
Reason given: Not approved by IRB
What was tested
Treatment tested
- AGEE cream
- 1% Steroid Cream
Placebo or sham
- topical placebo cream with no active ingredients
What it measured
Main measures
Histamine response after ethyl-α-guanida-methyl ethanoate (AGEE) and subcutaneous injection of glatiramer acetate
Three weeks
Who could take part
MS (type not specified) · 19 to 65
Inclusion Criteria: * Able to give informed consent * Between ages 19-65 * Laboratory supported diagnosis of multiple sclerosis * Currently treated with injectable GA, experiencing wheal and flare after injection Exclusion Criteria: * Unable to give informed consent * Treated with any other therapy for Multiple Sclerosis
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Participants with multiple sclerosis that are currently treated with glatiramer acetate (GA, Copaxone®) injections and have redness, pain, swelling, itching or a lump at the injection site will be recruited to examine histamine response of three topical treatments to reduce these symptoms.
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History
Started
Feb 2010
Main results due
Aug 2012
Finished
Aug 2012
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