Not yet recruitingNot a drug-phase studyRelapsing MSNCT04768777

What it found

Still running

No result yet.

What was tested

Treatment tested

  • Behavioural intervention for physical activity for multiple sclerosis (BIPAMS)

What it measured

Main measures

  • Change from baseline Sexual Dysfunction at 16 weeks

    Baseline, week 16

    Bladder, bowel and sexual functionPainQuality of life (reported by participants)

Other measures (3)

  • Change from baseline Sexual Dysfunction in MS at 16 weeks

    Baseline, week 16

    Bladder, bowel and sexual functionQuality of life (reported by participants)
  • Change from baseline Physical activity at 16 weeks

    Baseline, week 16

    Physical function
  • Change from baseline physical activity duration at 16 weeks

    Baseline, week 16

    Walking and mobilityPhysical function

Who could take part

Relapsing MS · 18 to 45

Inclusion Criteria: 1. Female 2. Diagnosed of relapsing remmiting multiple sclerosis 3. Relapse free in the past 30 days 4. Initial confirmation of sexual dysfunction (based on a semi-structured interview on sexual dysfunction diagnostic criteria in DSM-5) 5. Currently in a committed relationship with a partner who does not have a sexual disorder or sexual dysfunction 6. Internet and email access 7. Willingness to complete the questionnaires, wear the pedometer, and undergo randomization 8. Insufficient physical activity [not meeting current physical activity guidelines based on a health contribution score of less than 14 units from the Godin Leisure-Time Exercise Questionnaire (GLTEQ)] 9. Ability to ambulate without assistance [self-report and Patient-Determined Disease Steps (PDDS) score between 0 and 2 (mild ambulatory disability)] 10. Age between 18 and 45 years 11. English as primary language - Exclusion Criteria: 1. Moderate or high risk for contraindications of possible injury or death when undertaking strenous or maximal exercise -

As registered. Criteria can change, so ask the trial team or your neurologist.

Contact details on the registry

About this trial

In the sponsor's words

The prevalence of sexual dysfunction is higher among women with multiple sclerosis (MS) than women in the general population. The presence of sexual dysfunction is associated with decreased well-being and quality of life. There is limited research supporting pharmacological and other therapeutic approaches for managing sexual dysfunction in MS. Physical activity has beneficial effects on many of the consequences of MS, and physical activity represents a promising non-pharmacological approach for managing symptoms of sexual dysfunction in MS. The proposed research examines the effect of an Internet-delivered lifestyle physical activity intervention for improving sexual dysfunction in women with MS. The research proposed, if successful, will provide evidence for the efficacy of physical activity as a translatable approach for managing sexual dysfunction among women with MS.

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History

    1. Started

      Dec 2026

    2. Main results due

      Dec 2026

    3. Finished

      Dec 2026

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