AIM
What it found
No result yet.
What was tested
Treatment tested
- Immediate Autoimmune Intervention Mastery Course (AIM)
- Immediate Question and Answer sessions. (AIM Q and A sessions)
- Delayed Autoimmune Intervention Mastery Course (delayed AIM course)
- Delayed AIM Question and Answer sessions
What it measured
Main measures
Multiple Sclerosis 54 Quality of Life Mental Health (MS 54 QoL MH)
baseline to 3 months
Quality of life (reported by participants)Multiple Sclerosis 54 Quality of Life Mental Health (MS 54 QoL MH)
baseline to 6months
Quality of life (reported by participants)Multiple Sclerosis 54 Quality of Life Physical Health (MS 54 QoL PH)
baseline to 3 months
Quality of life (reported by participants)Multiple Sclerosis 54 Quality of Life Physical Health (MS 54 QoL PH)
baseline to 6 months
Quality of life (reported by participants)Short form 36 (SF 36)
baseline to 3 months
Short form 36 (SF 36)
baseline to 6 months
The Functional Assessment of Chronic Illness Therapy - Fatigue Scale (FACIT-FS):
baseline to 3 months
FatigueThe Functional Assessment of Chronic Illness Therapy - Fatigue Scale (FACIT-FS):
baseline to 6 months
Fatigue
Other measures (21)
Modified Fatigue Impact Scale
baseline to 3 months
FatigueModified Fatigue Impact Scale
baseline to 6 months
Fatiguevegetable and fruit intake
baseline to 3 months
vegetable and fruit intake
baseline to 6 months
added sugar intake
baseline to 3 months
added sugar intake
baseline to 6 months
calcium intake
baseline to 3 months
calcium intake
baseline to 6 months
Servings of whole grains consumed
baseline to 3 months
Servings of whole grains consumed
baseline to 6 months
Who could take part
Early (CIS/RIS) · 18 to 100
Inclusion Criteria: * self-reported multiple sclerosis * self-reported clinically isolated syndrome OR self-reported post-acute sequelae of COVID (PASC), also known as long COVID, with a confirmed laboratory test of COVID-19 infection, persisting fatigue and neuropsychiatric symptoms for longer than 6 months after confirmation of COVID diagnosis, OR self-reported diagnosis of fibromyalgia as documented by their treating specialist or primary care provider, Exclusion Criteria: -
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The goal of this project is to critically evaluate the effectiveness of using an online program to improve diet and self-care in patients with multiple sclerosis (MS), clinically isolated syndrome (CIS), fibromyalgia, post acute sequela of covid, and cancer in remission with persisting fatigue.
Papers
Results
Evaluation of a web-based program for the adoption of wellness behaviors to self-manage fatigue and improve quality of life among people with multiple sclerosis: A randomized waitlist-control trial.Mult Scler Relat Disord · 2023
Background
Wahls TL, Chenard CA, Snetselaar LG. Review of Two Popular Eating Plans within the Multiple Sclerosis Community: Low Saturated Fat and Modified Paleolithic. Nutrients. 2019 Feb 7;11(2):352. doi: 10.3390/nu11020352.Background
Wahls T, Scott MO, Alshare Z, Rubenstein L, Darling W, Carr L, Smith K, Chenard CA, LaRocca N, Snetselaar L. Dietary approaches to treat MS-related fatigue: comparing the modified Paleolithic (Wahls Elimination) and low saturated fat (Swank) diets on perceived fatigue in persons with relapsing-remitting multiple sclerosis: study protocol for a randomized controlled trial. Trials. 2018 Jun 4;19(1):Background
Chenard CA, Rubenstein LM, Snetselaar LG, Wahls TL. Nutrient Composition Comparison between a Modified Paleolithic Diet for Multiple Sclerosis and the Recommended Healthy U.S.-Style Eating Pattern. Nutrients. 2019 Mar 1;11(3):537. doi: 10.3390/nu11030537.Background
Titcomb TJ, Bisht B, Moore DD 3rd, Chhonker YS, Murry DJ, Snetselaar LG, Wahls TL. Eating Pattern and Nutritional Risks among People with Multiple Sclerosis Following a Modified Paleolithic Diet. Nutrients. 2020 Jun 20;12(6):1844. doi: 10.3390/nu12061844.Background
Wahls TL, Titcomb TJ, Bisht B, Eyck PT, Rubenstein LM, Carr LJ, Darling WG, Hoth KF, Kamholz J, Snetselaar LG. Impact of the Swank and Wahls elimination dietary interventions on fatigue and quality of life in relapsing-remitting multiple sclerosis: The WAVES randomized parallel-arm clinical trial. Mult Scler J Exp Transl Clin. 2021 Jul 31;7(3):20552173211035399. doi: 10.1177/20552173211035399. eCoBackground
Lee JE, Titcomb TJ, Bisht B, Rubenstein LM, Louison R, Wahls TL. A Modified MCT-Based Ketogenic Diet Increases Plasma beta-Hydroxybutyrate but Has Less Effect on Fatigue and Quality of Life in People with Multiple Sclerosis Compared to a Modified Paleolithic Diet: A Waitlist-Controlled, Randomized Pilot Study. J Am Coll Nutr. 2021 Jan;40(1):13-25. doi: 10.1080/07315724.2020.1734988. Epub 2020 MarBackground
Bisht B, Darling WG, Grossmann RE, Shivapour ET, Lutgendorf SK, Snetselaar LG, Hall MJ, Zimmerman MB, Wahls TL. A multimodal intervention for patients with secondary progressive multiple sclerosis: feasibility and effect on fatigue. J Altern Complement Med. 2014 May;20(5):347-55. doi: 10.1089/acm.2013.0188. Epub 2014 Jan 29.Background
Bisht B, Darling WG, White EC, White KA, Shivapour ET, Zimmerman MB, Wahls TL. Effects of a multimodal intervention on gait and balance of subjects with progressive multiple sclerosis: a prospective longitudinal pilot study. Degener Neurol Neuromuscul Dis. 2017 Jun 26;7:79-93. doi: 10.2147/DNND.S128872. eCollection 2017.Background
Irish AK, Erickson CM, Wahls TL, Snetselaar LG, Darling WG. Randomized control trial evaluation of a modified Paleolithic dietary intervention in the treatment of relapsing-remitting multiple sclerosis: a pilot study. Degener Neurol Neuromuscul Dis. 2017 Jan 4;7:1-18. doi: 10.2147/DNND.S116949. eCollection 2017.
Loading reviews and guidelines…
History
Started
Dec 2021
Main results due
Dec 2027
Finished
Dec 2027
Assembled by software from public sources and not checked by people. Each record links to its source. Report an error