Stopped earlyNot a drug-phase studyOptic neuritisNCT05353413

What it found

Stopped early

The trial ended early for another reason (see below).

Reason given: Study terminated prematurely due to lack of funding. Seven patients with optic neuropathies were enrolled; no healthy volunteers were enrolled.

What was tested

Treatment tested

  • Neuroimaging
  • VEP - visual evoked potential
  • Ophthalmology examination.

What it measured

Main measures

  • sigma parameter

    Periprocedural (single MRI examination)

    Brain volume loss

Who could take part

Optic neuritis · 18 and over

Inclusion Criteria: * Patient group: optic neuropathy. * Planned healthy control group: healthy volunteers without concomitant diseases. Exclusion Criteria: - Common contraindications to MRI (presence of pacemaker, non-MRI-safety or claustrophobia).

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

The aim of the project is to create a new, non-invasive and safe protocol for the early diagnosis of various types of optic neuropathies with the use of diffusion magnetic resonance imaging

Papers

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    History

      1. Started

        Jan 2020

      2. Main results due

        Mar 2026

      3. Finished

        Mar 2026

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