Home-based Balance Training in Adults With Multiple Sclerosis
What it found
A paper reports the results; we have not read it yet. See Papers below.
What was tested
Treatment tested
- Home-based balance training
What it measured
Main measures
Feasibility outcome: Process
From enrollment to completion of posttest (12weeks)
Physical functionQuality of life (reported by participants)FeasibilityFeasibility outcome: Resources
From enrollment to completion of posttest (12weeks)
Physical functionFeasibilityFeasibility outcome: Management
From enrollment to completion of posttest (12weeks)
FeasibilityFeasibility outcome: Participant burden/satisfaction
After completion of posttest (12weeks)
Quality of life (reported by participants)FeasibilityFeasibility outcome: Adverse event
From enrollment to completion of posttest (12weeks)
SafetyFeasibilityFeasibility outcome: Intervention acceptability
From enrollment to completion of posttest (12weeks)
Physical functionFeasibilityFeasibility outcome: exercise intensity acceptability/compliance
From enrollment to completion of posttest (12weeks)
Physical functionFeasibility
Other measures (11)
Changes in balance as measured by Timed Up and Go/Dual-task Timed Up and Go
Baseline and after completion of an intervention (12weeks)
Thinking and memoryWalking and mobilityChanges in functional mobility as measured by 5-time sit-to-stand
Baseline and after completion of an intervention (12weeks)
Walking and mobilityChanges in static balance as measured by4-stage static balance tests
Baseline and after completion of an intervention (12weeks)
Walking and mobilityChanges in cognitive function as measured by Brief International Cognitive Assessments for MS (BICAMS)
Baseline and after completion of an intervention (12weeks)
Thinking and memoryChanges in community mobility perception as measured by Environmental Analysis of Mobility Questionnaire (EAMQ)
Baseline and after completion of an intervention (12weeks)
Thinking and memoryWalking and mobilityBladder, bowel and sexual functionChanges in fear of falling as measured by Fall Efficacy Scale-International (FES-I)
Baseline and after completion of an intervention (12weeks)
Walking and mobilityChanges in self-reported walking disability as measured by Multiple Sclerosis Walking Scale-12v2 (MSWS-12v2)
Baseline and after completion of an intervention (12weeks)
Walking and mobilityChanges in self-reported dual-tasking difficulty as measured by Dual-task Impact on Daily-Living Activities Questionnaire (DIDA-Q)
Baseline and after completion of an intervention (12weeks)
Changes in self-reported fatigue as measured by Fatigue Scale for Motor and Cognitive Functions (FSMC)
Baseline and after completion of an intervention (12weeks)
Thinking and memoryFatigueChanges in Real-world ambulation metrics as measured by tri-axial accelerometer
Baseline and after completion of an intervention (12weeks)
Walking and mobility
Who could take part
MS (type not specified) · 18 to 75
Inclusion Criteria: * Physician-diagnosed MS * Ages 18-75 years * Patient Determined Disease Steps (PDDS) scale score between 2-5 (i.e., gait disability-late cane) * Able to participate in exercise (i.e., one or fewer affirmatives on the Physical Activity Readiness Questionnaire (PAR-Q+)) * Have a webcam on a device at least the size of a full tablet (i.e., larger than a smartphone) * Have an exercise supporter (e.g., spouse or family member) who is willing to participate in the intervention * Not currently participating in any balance-related exercise program Exclusion Criteria: * Cognitively unable to read and sign informed consent form and follow verbally delivered screening assessment * Unable to communicate in English
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
This single-group pretest-posttest study aims to examine the feasibility domains in response to 12 weeks of home-based balance training in persons with multiple sclerosis (MS). The feasibility domains include 1) process (e.g., recruitment, attendance, adherence rate), 2) resources (e.g., total monetary costs), 3) management (e.g., assessment time), and 4) scientific outcomes (adverse events, intervention acceptability, satisfaction, treatment effects). Moreover, this study aims to evaluate physical function (i.e., balance, mobility, dual-task ability), cognitive function (i.e., cognitive processing speed, verbal memory, visuospatial memory), real-world ambulation (i.e., gait speed, gait variability, gait quantity), and self-report questionnaires (fatigue, fear of falling, walking disability, dual-tasking difficulty). Our proposed intervention is expected to deliver a feasible and accessible exercise modality for balance and cognitive improvement in persons with multiple sclerosis.
Papers
Loading reviews and guidelines…
History
Started
Jul 2024
Main results due
Mar 2025
Finished
May 2025
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