ProChocolate
We could not find results for this trial
I know where the results areWhat it found
We found no results in the registry or in papers.
This trial finished 22 months ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- Bouchard Belgian Dark Chocolate Probiotic Napolitains, containing bifidobacterium longum
What it measured
Main measures
peripheral blood mononuclear cell (PBMC) profile: Change in Regulatory T (Treg) cells
baseline (week 0) to week 6
peripheral blood mononuclear cell (PBMC) profile: Change in T helper (TH) cells
baseline (week 0) to week 6
peripheral blood mononuclear cell (PBMC) profile: Change in T helper Th17 cells
baseline (week 0) to week 6
Change in serum microbial metabolites
baseilne (week 0) to week 6
Other measures (4)
Change in Modified Fatigue Impact Scale-5 Impact Scale
week 0, week 6
FatigueQuality of life (reported by participants)Change in Patient-Determined Disability Scale (PDDS)
week 0, week 6
Quality of life (reported by participants)Change in Bowel Control Scale
week 0, week 6
Bladder, bowel and sexual functionQuality of life (reported by participants)Change in Multiple Sclerosis Rating Scale- Revised (MSRS-R) Patient-Determined Disease Steps Scale
week 0, week 6
Quality of life (reported by participants)
Who could take part
MS (type not specified) · 18 to 45
Inclusion Criteria: * Multiple Sclerosis (MS) subjects, first-degree relatives of MS subjects, or healthy controls * Age 18-45 Exclusion Criteria: * diabetes * tree nut allergy * pregnancy
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The goal of this study is to assess the effects of probiotics on persons with multiple sclerosis (MS), persons at higher genetic risk for MS (first degree family members of persons with MS), and healthy controls. Participants will be asked to consume probiotic containing chocolates (Bouchard Belgian Dark Chocolate Probiotic Napolitains containing 10 billion CFUs of bifidobacterium longum per day) for 6 weeks. Participants will undergo blood draws before and after the 6 weeks of probiotic containing chocolate and microbial metabolites and immune markers will be compared before and after the probiotics, as well as between groups.
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History
Started
Jun 2024
Main results due
Dec 2024
Finished
Dec 2024
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