RecruitingNot a drug-phase studyMS (type not specified)NCT07137624

What it found

Still running

No result yet.

What was tested

Treatment tested

  • Action Observation + Motor Imagery
  • Nature Video

What it measured

Main measures

  • Change in Tibialis Anterior and Gastrocnemius Medialis Muscle Activity Amplitude

    Before and immediately after the intervention

    Walking and mobility
  • Change in Tibialis Anterior and Gastrocnemius Medialis Muscle Activity Onset Latency

    Before and immediately after the intervention.

    Myelin repairWalking and mobility
  • Change in Step Length

    Before and immediately after the intervention

    Walking and mobility
  • Change in Step Time

    Before and immediately after the intervention

    Walking and mobility
  • Change in Step Width

    Before and immediately after the intervention

    Walking and mobility
  • Change in Double Support Period

    Before and immediately after the intervention

    Walking and mobility
  • Change in Gait Velocity

    Before and immediately after the intervention

    Walking and mobility
  • Change in Cadence

    Before and immediately after the intervention

    Walking and mobility

Other measures (8)

  • Motor Imagery Vividness

    Baseline only

  • Mental Chronometry Ratio

    Baseline only

    Walking and mobility
  • Limb Laterality Recognition Performance

    Baseline only

    Thinking and memory
  • Cognitive Status

    Baseline only

    Thinking and memory
  • Fatigue Level

    Baseline only

    Fatigue
  • Anxiety and Depression

    Baseline only

    Mood and sleep
  • Disability Level

    Baseline only

    Disability progressionVisionWalking and mobility
  • Visual Acuity

    Baseline only

    Vision

Who could take part

MS (type not specified) · 18 and over

Inclusion Criteria: * A confirmed diagnosis of multiple sclerosis (MS) by a neurologist * No history of relapse within the past 3 months and not currently experiencing a relapse * A score of 24 or higher on the standardized Mini Mental State Examination Exclusion Criteria: * Presence of serious health conditions affecting the muscles, heart, lungs, or metabolism that could interfere with participation * History of other neurological disorders, head injury, or chronic psychiatric conditions * Chronic pain lasting longer than six months * Significant muscle stiffness in the legs that may affect EMG recordings * Hearing difficulties * Vision problems as determined by the Snellen visual acuity test

As registered. Criteria can change, so ask the trial team or your neurologist.

Contact details on the registry

About this trial

In the sponsor's words

This study will investigate whether mentally simulating walking movements while watching others walk can improve walking performance in individuals with Multiple Sclerosis (MS). Participants will be divided into two groups: one group will watch walking videos and imagine themselves walking, while the other group will watch nature scenes. The study will measure muscle activity and walking patterns to assess the effects. The results may help support the use of mental practice techniques to improve mobility in people with MS.

Papers

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History

    1. Started

      Jan 2026

    2. Main results due

      Nov 2026

    3. Finished

      Nov 2026

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