MS
What it found
No result yet.
What was tested
Treatment tested
- Augmented Reality Exercises
What it measured
Main measures
Gait Velocity- single-task (BTS GAITLAB)
six weeks
Walking and mobilityGait velocity during dual-task walking (m/s)
6 weeks
Thinking and memoryWalking and mobility
Other measures (18)
Balance - Berg Balance Scale (BBS)
Six weeks
Walking and mobilityActivities-specific Balance Confidence (ABC) Scale score (0-100%)
6 weeks
Walking and mobilityFive Times Sit-to-Stand test time (seconds)
6 weeks
Functional Mobility Scale (FMS) rating
6 weeks
Walking and mobilityBiodex Balance System stability index (unit per device output)
6 weeks
Walking and mobilityDaily step count measured by FIBION (steps/day)
6 weeks
Physical functionModified Physical Activity Scale (M-PAS) score
6 weeks
Physical functionFalls Efficacy Scale-International (FES-I) total score
6 weeks
Walking and mobilityModified Fatigue Impact Scale (MFIS) total score
6 weeks
FatigueShort Form-36 (SF-36) health-related quality of life score
6 weeks
Quality of life (reported by participants)
Who could take part
Relapsing and progressive · 18 and over
Inclusion Criteria: * Neurologist-confirmed diagnosis of MS according to the revised McDonald criteria and PDDS score of ≤6 * Age above 18 years; * Affected by relapsing remitting and secondary progressive MS * Successful completion of Physical Activity Readiness Questionnaire (PAR-Q) * Presence of mild/moderate cognitive impairment (Montreal Cognitive Assessment - MoCA >18) * Ambulatory for indoor and outdoor mobility with or without an assistive device but without physical assistance Exclusion Criteria: * Acute illness or injury that would prevent safe participation in an exercise program * Presence of any other neurological conditions (e.g., stroke), * Presence of severe psychiatric illness other than anxiety or depression * According to the Diagnostic and Statistical Manual of Mental Disorders, 5th -Edition (DSM- V), * Presence of disabling sensory alterations (i.e. auditory and visual disturbances) * Relapse in the 3 months before enrollment * Current engagement in 3 days a week or more of moderate/vigorous exercise
As registered. Criteria can change, so ask the trial team or your neurologist.
Contact details on the registryAbout this trial
In the sponsor's words
Multiple Sclerosis (MS) is the most common NDD affecting young people worldwide. MS can seriously affect quality of life and hinder daily functional activities. Therefore, living with MS is a daunting task for both patients and their families. With the prediction of an increase in life expectancy, it is also expected that MS will pose major challenges to healthcare providers in the UAE and globally in terms of its clinical management and financial implications. This proposed project aims to develop structured AR scenarios that integrate dual-tasking exercises commonly used in MS physiotherapy, specifically designed to meet the needs of PwMS. The primary goal is to evaluate the feasibility, acceptability, and potential benefits of these AR scenarios as a rehabilitation tool for PwMS.
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History
Started
Aug 2026
Main results due
Mar 2028
Finished
Sept 2028
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