No clear answer
Spasticity: improve symptoms or function in relapsing and progressive MS
relapsing and progressive MS · Spasticity
Trials have tried this, but none was a controlled phase 2 or 3 trial with a readable result.
- Trials
- 3
- Running now
- 0
- Controlled phase 2/3 trials
- 0
- People in controlled trials
- 0
No controlled trial has reported a result yet.
Other linked trials: 3
Dose comparisons, trials against another medicine, add-on trials, phase 1 and uncontrolled studies. They are listed below but do not set the status.
Trials
Other linked trials: 3
These linked trials do not set the status.
- Safety of Xeomin for Lower Limb Spasticity in Multiple Sclerosis PatientsResult in a paper, not read yet
Phase 4 · 2013 · Placebo-controlled
Phase 3 · 2018 · Not randomised
- Safety and Preliminary Effectiveness of AV650 in Patients With Spasticity Associated With Multiple SclerosisStopped, other reason
Phase 2 · 2007 · Not randomised
The deciding phase and counts come from the Trial Bank’s fixed rules.
Lab evidence
Lab studies in animals or cells. Results in animals often do not hold in people, and these studies never change the status of an idea.
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History
- 2026-10-28Trials: 11 → 3
- 2026-10-28Status changed from Being tested to No clear answer
- 2026-10-27First listed as Being tested
Related hypotheses
- Spasticity: improve symptoms or function in MS (type not specified)
- Arbaclofen placarbil: improve symptoms or function in relapsing and progressive MS
- Arbaclofen: improve symptoms or function in relapsing and progressive MS
- Botulinum toxin type a: improve symptoms or function in relapsing and progressive MS
- Cannabidiol: improve symptoms or function in relapsing and progressive MS
- Dronabinol: improve symptoms or function in relapsing and progressive MS
- Nabiximols: improve symptoms or function in relapsing and progressive MS
- Onabotulinumtoxina: improve symptoms or function in relapsing and progressive MS
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