Rituximab
How it works: Removing B cells →
In development for MS or related diseases. No approval for these conditions is recorded in the bank.
- Molecule type
- Antibody
- Mechanism (ChEMBL)
- B-lymphocyte antigen CD20 binding agent
- Targets
- B-lymphocyte antigen CD20
Approvals
None recorded.
Safety communications
None recorded.
Trials
Key trials
Large trials with a reported result on their main goal.
- RIFUND-MS
Completed · Phase 3 · Relapsing MS · Main goal met
- Azathioprine, phase 2 / phase 3
Completed · Phase 2 / Phase 3 · NMOSD · Main goal met
- OLYMPUS
Completed · Phase 2 / Phase 3 · Progressive MS · Main goal not met
Running now
- HiHat
Recruiting · Phase 2 · Relapsing MS · ongoing
- BEST-NMOSD
Recruiting · Phase 4 · NMOSD · ongoing
- IDAR
Recruiting · Phase 3 · MOGAD · ongoing
- Rituximab, phase 2
Recruiting · Phase 2 · Progressive MS · ongoing
- TRIO
Recruiting · Phase 3 · Relapsing and progressive · ongoing
- Rituximab, phase 4
Running, not recruiting · Phase 4 · Relapsing MS · ongoing
- Rituximab, phase 3
Recruiting · Phase 3 · Relapsing MS · ongoing
- DanNORMS
Running, not recruiting · Phase 3 · Relapsing and progressive · ongoing
- Ocrelizumab, phase 3
Running, not recruiting · Phase 3 · Relapsing MS · ongoing
- STOP-I-SEP
Running, not recruiting · Phase 3 · Progressive MS · ongoing
Other trials (23)
Completed small trials, dose-finding studies and trials in other diseases.
- Rituximab, phase 1
Status unknown · Phase 1 · MS (type not specified) · no_result_found
- ATTEND
Withdrawn · Phase 2 / Phase 3 · NMOSD · stopped_other
- NOR-MS
Completed · Phase 3 · Relapsing MS · no_result_found
- NOR-MS
Completed · Phase 3 · Relapsing MS · no_result_found
- RIDOSE-MS
Status unknown · Phase 3 · Relapsing MS · no_result_found
- Rituximab, phase 2
Completed · Phase 2 · MS (type not specified) · no_result_found
- Glatiramer acetate, phase 2 / phase 3
Completed · Phase 2 / Phase 3 · Progressive MS · no_result_found
- Rituximab, phase 4
Completed · Phase 4 · Relapsing MS · no_result_found
- EFFRITE
Completed · Phase 2 · Progressive MS · Main goal not met
- Rituximab, phase 1
Completed · Phase 1 · Progressive MS · no_result_found
For information only, not medical advice. Talk to your neurologist before changing treatment.
Hypotheses involving this medicine
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Lab studies
Lab studies in animals or cells. Results in animals often do not hold in people, and these studies never change the status of an idea.
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