Failed in phase 2
Fumarates / NRF2: protect nerve tissue in primary progressive MS
primary progressive MS · Fumarates / NRF2
Controlled phase 2 trials did not meet their main goal for this group.
- Trials
- 1
- Running now
- 0
- Controlled phase 2/3 trials
- 1
- People in controlled trials
- 54
How the verdict was reached
Negative in phase 2
| Trial | Phase | Participants | Started | Result | Counted |
|---|---|---|---|---|---|
| FUMAPMS | Phase 2 | 54 | 2016 | Missed its main goal Mean change in CSF concentrations of NFL did not differ between groups (mean difference 99 ng/L; 95% CI -292 to 491 ng/L). Paper abstract | Counted |
Counted: 1. Will count later: 0. Not counted: 0.
Lab evidence
Lab studies in animals or cells. Results in animals often do not hold in people, and these studies never change the status of an idea.
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History
- Oct 2026First listed as Failed in phase 2
Related hypotheses
Assembled by software from public sources.