Being tested
Metformin: slow disability worsening in primary progressive MS
primary progressive MS · Mitochondrial / oxidative stress
Trials are running now and no controlled trial has a readable result yet.
- Trials
- 2
- Running now
- 2
- Controlled phase 2/3 trials
- 1
- People in controlled trials
- 120
How the verdict was reached
No result yet
| Trial | Phase | Participants | Started | Result | Counted |
|---|---|---|---|---|---|
| MACSiMiSE-BRAIN | Phase 2 | 120 | 2023 | Still running | Will count when it reports |
| OCTOPUS | Phase 3 | 1,200 | 2023 | Still running | Not counted: not randomised |
Counted: 0. Will count later: 1. Not counted: 1.
Lab evidence
Lab studies in animals or cells. Results in animals often do not hold in people, and these studies never change the status of an idea.
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History
- Oct 2026First listed as Being tested
Related hypotheses
- Acetylcysteine: protect nerve tissue in primary progressive MS
- Thioctic acid: protect nerve tissue in primary progressive MS
- Biotin: slow disability worsening in primary progressive MS
- Metformin: slow disability worsening in secondary progressive MS
- Thioctic acid: slow disability worsening in primary progressive MS
Assembled by software from public sources.