Being tested
BTK inhibition (B cells and microglia): reduce relapses and new lesions in relapsing and progressive MS
relapsing and progressive MS · BTK inhibition (B cells and microglia)
Trials are running now and no controlled trial has a readable result yet.
- Trials
- 9
- Running now
- 4
- Controlled phase 2/3 trials
- 0
- People in controlled trials
- 0
No controlled trial has reported a result yet.
Other linked trials: 9
Dose comparisons, trials against another medicine, add-on trials, phase 1 and uncontrolled studies. They are listed below but do not set the status.
Trials
Other linked trials: 9
These linked trials do not set the status.
Phase 3 · 2024 · Compared with teriflunomide
- CLOU064C12301Ongoing
Phase 3 · 2021 · Compared with teriflunomide
- CLOU064C12302Ongoing
Phase 3 · 2021 · Compared with teriflunomide
- Phase III Study of Evobrutinib in RMS (EVOLUTION RMS 2)Missed main goal
Phase 3 · 2020 · Compared with teriflunomide
- Phase III Study of Evobrutinib in RMS (EVOLUTION RMS 1)Missed main goal
Phase 3 · 2020 · Compared with teriflunomide
- Phase III Study of Evobrutinib in RMS (EVOLUTION MS2)Stopped, other reason
Phase 3 · 2019 · Compared with interferon beta-1a
- Phase III Study of Evobrutinib in RMS (EVOLUTION MS1)Stopped, other reason
Phase 3 · 2019 · Compared with interferon beta-1a
- RemiSevenOngoing
Phase 2 · 2027 · Not randomised
- A Study of Efficacy and Safety of M2951 in Participants With Relapsing Multiple SclerosisStopped: not working
Phase 2 · 2017 · Compared with dimethyl fumarate
The deciding phase and counts come from the Trial Bank’s fixed rules.
Lab evidence
Lab studies in animals or cells. Results in animals often do not hold in people, and these studies never change the status of an idea.
Loading lab studies…
Loading reviews and guidelines…
History
- 2026-10-27First listed as Being tested
Related hypotheses
Assembled by software from public sources and not checked by people. Each record links to its source. Report an error