No clear answer
Metformin: reduce relapses and new lesions in primary progressive MS
primary progressive MS · Mitochondrial / oxidative stress
Trials have tried this, but none was a controlled phase 2 or 3 trial with a readable result.
- Trials
- 1
- Running now
- 0
- Controlled phase 2/3 trials
- 0
- People in controlled trials
- 0
How the verdict was reached
No result yet
| Trial | Phase | Participants | Started | Result | Counted |
|---|---|---|---|---|---|
| Metformin, phase 1 | Early phase 1 | 23 | 2022 | Paper found, not read | Not counted: phase 1 or phase 4 |
Counted: 0. Will count later: 0. Not counted: 1.
Lab evidence
Lab studies in animals or cells. Results in animals often do not hold in people, and these studies never change the status of an idea.
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History
- Oct 2026First listed as No clear answer
Related hypotheses
- Acetylcysteine: protect nerve tissue in primary progressive MS
- Thioctic acid: protect nerve tissue in primary progressive MS
- Biotin: slow disability worsening in primary progressive MS
- Thioctic acid: slow disability worsening in primary progressive MS
- Metformin: reduce relapses and new lesions in secondary progressive MS
- Metformin: reduce relapses and new lesions in MS (type not specified)
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