Baclofen
How it works: Treating relapses and symptoms →
Fleqsuvy
EU: Approved nationally (not via EMA)US: FDA approved 2022
- Molecule type
- Small molecule
- Mechanism (ChEMBL)
- GABA-B receptor agonist
- Targets
- GABA-B receptor
Approvals
- USFleqsuvy · Approved4 February 2022 Source
Safety communications
None recorded.
Most-reported side effects (FDA reports)
Reports to the FDA's adverse event system (FAERS) show what people and doctors reported while taking the medicine. They do not prove the medicine caused it, and they are not rates.
94,083 reports in total, 62,876 marked serious.
- Fatigue6,569
- Pain6,467
- Drug ineffective6,124
- Fall5,842
- Nausea5,073
- Headache4,764
- Gait disturbance4,338
- Off label use4,122
- Dizziness3,840
- Muscle spasms3,808
Trials
Other trials (3)
Completed small trials, dose-finding studies and trials in other diseases.
- A STUDY OF THE SAFETY AND EFFECTS OF BACLOFEN ER CAPSULES (GRS) IN SUB
Completed · Phase 3 · MS (type not specified) · No results found
- IPX056 in Subjects With Established Spasticity Resulting From Multiple
Completed · Phase 3 · MS (type not specified) · No results found
- A Multicenter, Open-label Randomized Crossover Trial to Assess Subject
Completed · Phase 3 · MS (type not specified) · No results found
For information only, not medical advice. Talk to your neurologist before changing treatment.
Hypotheses involving this medicine
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Lab studies
Lab studies in animals or cells. Results in animals often do not hold in people, and these studies never change the status of an idea.
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