Klassische Konditionierung immunologischer Reaktionen bei Patienten mi
Klassische Konditionierung immunologischer Reaktionen bei Patienten mit Multipler Sklerose während Mitoxantrontherapie
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- Mitoxantrone
What it measured
Main measures
rate of apotosis of B-cell as measured by FACS
Immune response
Who could take part
Progressive MS
Show the full criteria
Inclusion criteria
Inclusion: secondary chronic progressive multiple sclerosis Exclusion: malignant MS, acute relapse, drug-treated psychiatric disease, allergy against methylenblue, severe renal function disturbance, vaccination within the last 4 weeks, pregnancy, hypersensitivity against mitoxantrone, natriummetabisulfite, severe ongoing infections, cardiac diseases, renal and liver insufficiency
Exclusion criteria
Not separately supplied in the registry.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
To clarify the immunological effects of a placebo-infusion with methylenblue versus the drug mitoxantrone in an immune conditioning setting
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Paper found, not read
History
Started
Nov 2007