Immune tolerance induction in MS patients with neutralizing antibodies against interferon-beta

CompletedPhase 4MS (type not specified)2009-013284-19

What it found

No results found

We found no results in the registry or in papers.

What it measured

Main measures

  • Non-respond of MxA RNA, a biomarker for interferon-beta bioavailability, after 2 infusions of 48 MIU interferon-beta.

    Blood or spinal fluid markersImmune responseHow the body handles the medicine

Who could take part

MS (type not specified)

Show the full criteria

Inclusion criteria

Inclusion: diagnosed multiple sclerosis Exclusion: < 18 years old

Exclusion criteria

Not separately supplied in the registry.

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

How many multiple slerosis patients show a reduction of the neutralizing antibodies < 100 neutralizing units after 3 months of weekly intravenous interferon-beta infusion.

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History

    1. Started

      Nov 2009

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