Inflammation of the optic nerve and early treatment with prednisolone.
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- Methylprednisolone
Glucocorticoid receptor agonist
What it measured
Main measures
1) Retinal nerve fiber layer thickness.
Retina scans (OCT)
Other measures (1)
Contrast sensitivity, colour vision, visual field, appearance of optic nerve papil, vascular changes in retina, changes in retina's inner nuclear layer, visual evoked potentials, MRI changes in brain and spinal cord, NMO-IgG in blood, Extended Disability Status Scale (EDSS) score.
Disability progressionMRI lesionsMyelin repairVision
Who could take part
Optic neuritis
Inclusion: 1) Optic neuritis diagnosed by ophthalmologist. Exclusion: 1) Persons not of age, and persons without ability to give informed concent.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
To see if early treatment of acute optic neuritis with high-dosis intravenous Solu-medrol, has effect on visual function at follow-up 6 months and 12 months later.
Papers
Loading reviews and guidelines…
Related trials
- PIONEER-1
Phase 3 · Recruiting
Still running
- TIMELY-PLEX
Phase 3 · Recruiting
Still running
- Retrobulbar Methylprednisolone as Adjunctive Treatment in…
Phase 2 / Phase 3 · Status unknown
No result found
- ACUITY
Phase 2 · Completed
Result in a paper, not read yet
- ACHTAR
Early phase 1 · Completed
Result in a paper, not read yet
- Optic Neuritis Recovery After Oral or IV Corticosteroids
Phase 2 / Phase 3 · Completed
Result in a paper, not read yet
History
Started
Jul 2012
Assembled by software from public sources and not checked by people. Each record links to its source. Report an error