ACHTAR
What it found
A paper reports the results; we have not read it yet. See Papers below.
What was tested
Treatment tested
- Corticotropin
Melanocortin receptor 2 agonist
What it measured
Main measures
Neuro-protection
12 months
Vision
Other measures (1)
Preservation of retinal nerve fiber layer.
12 months
Retina scans (OCT)
Who could take part
Optic neuritis · 18 and over
Inclusion Criteria: * unilateral acute demyelinating optic neuritis * Able to provide informed consent * age 18 or older * can perform the above listed electrophysiologic diagnostic testing * can perform high and low contrast visual acuity and visual field perimetry Exclusion Criteria: * prior diagnosis of remitting/relapsing multiple sclerosis(RRMS) * secondary progressive MS(SPMS) * primary progressive MS (PPMS) * undergoing treatment with medications approve for treatment of RRMS(except corticosteroids for a condition not involving central nervous system demyelination) * prior diagnosis of systemic lupus erythematosis * mixed connective tissue disease * vasculitis * sarcoidosis * neuro-myelitis optica
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The goal of the study is to determine the earliest structural changes in the optic nerve during the acute event and during the twelve months of recovery following Acthar treatment.
Papers
Loading reviews and guidelines…
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History
Started
Nov 2013
Main results due
Dec 2016
Finished
Dec 2016
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