The effect of balance training on balance in people with multiple scle
The effect of balance training on postural control in people with multiple sclerosis using the CAREN virtual reality system: a pilot randomized controlled trial
What it found
A paper reports the results; we have not read it yet. See Papers below.
What it measured
Main measures
Center of pressure (CoP) trajectories are measuring using posturography measurements taken from the Zebris FDM-T Treadmill data at baseline and 6 weeks.
Other measures (1)
1. Stability is measured using the Functional Reach Test (FRT) at baseline and 6 weeks 2. Balance is measured using the Berg Balance Test (BBS) at baseline and 6 weeks 3. Ability to change directions while stepping is measured using the Four Square Step Test (FSST) at baseline and 6 weeks 4. Fear of falling is measured using the Falls Efficacy Scale International (FES-I) at baseline and 6 weeks
Walking and mobility
Who could take part
Relapsing MS · EDSS 3.0 to 6.0
Show the full criteria
Inclusion criteria
Inclusion: 1. Diagnosis of definite relapsing-remitting MS according to the revised McDonald criteria 2010 2. Aged between 25 and 55 years 3. Moderate neurological disability as scored by the expanded disability status scale (EDSS), ranging from 3.0 to 6.0 inclusive with a pyramidal functional score of at least 3 Exclusion: 1. MS clinical relapse or treatment with corticosteroid therapy within 6-months prior to examination 2. Patients experiencing major depression or cognitive decline 3. Orthopedic disorders that could negatively affect balance 4. Pregnancy 5. Blurred vision 6. Cardiovascular disorders
Exclusion criteria
Not separately supplied in the registry.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Background and study aims Multiple sclerosis (MS) is one of the most common diseases of the central nervous system (brain and spinal cord). Healthy nerves are coated in a fatty casing (myelin sheath) which helps messages to travel quickly and smoothly along nerves. When a person is suffering from MS, the immune system, which normally helps to protect against infection, attacks the myelin sheath, stripping it from the nerves (demyelination). This demyelination means that messages cannot travel along the nerves effectively, causing a range of disabilities. Around 85% of MS sufferers are diagnosed with the relapsing remitting type. This is where the sufferer has sudden flare-ups of symptoms (relapses) followed by periods where the symptoms are very mild or disappear completely. Many people suffering from MS suffer from problems with balance. The aim of this study is to look at the effects of training with a new virtual reality system on balance in people with MS and compare it with traditional physical therapy. Who can participate? Adults aged between 25 and 55 who have been diagnosed with relapsing-remitting MS and are moderately disabled. What does the study involve? Participants are randomly allocated to one of two groups. Those in the first group complete a 6 week virtual reality training program. The participants take part in two sessions a week which include around 30 minutes of balance training. Participants are asked to stand of a moving platform and look at a screen with a road on it. The road itself includes flat, bumpy and tilting sections and the moving platform moves in sync with the image of the road on the screen (i.e. when the road tilts, the platform tilts). Participants are asked to “walk” along the road whilst keeping their balance. Participants in the second group take part in a conventional exercise program (traditional physical therapy), which consists of balancing on an uneven surface (foam), an unstable base (wobble board) and by catching balls thrown at them from different directions but stepping forward or sideways. At the study of the study and then again at the end of the 6 week training programs, participants in both groups complete a number of assessments and questionnaires in order to find out if their balance has improved. What are the possible benefits and risks of participating? Participants may benefit from improved balance as a result of taking part in the study. There are no significant risks of taking part, however some participants may experience nausea because of the moving platform used. Where is the study run from? Sheba Medical Center (Israel) When is the study starting and how long is it expected to run for? June 2013 to June 2015 Who is funding the study? National Multiple Sclerosis Society (USA) Who is the main contact? Dr Alon Kalron alkalron@gmail.com
Papers
Loading reviews and guidelines…
History
Started
Jun 2014
Finished
Jun 2015