Effects of a cognitive-behavioural mindfulness intervention upon quali
Effects of a cognitive-behavioural mindfulness intervention upon quality of life, depression and fatigue among multiple sclerosis (MS) patients
What it found
A paper reports the results; we have not read it yet. See Papers below.
What it measured
Main measures
1. Quality of life: Hamburg Quality of Life Questionnaire in Multiple Sclerosis and Profile Quality of Life in Chronic Disorder 2. Modified Fatigue Impact Scale 3. Center for Epidemiological Studies Depression Scale Timepoints of assessment: pre-Intervention, post-intervention and 6-month post-intervention.
FatigueMood and sleepQuality of life (reported by participants)
Other measures (1)
1. Multiple Sclerosis Inventory of Cognition 2. Personal Goal Attainment Scale 3. Visual Analogue Quality of Life Scale 4. Spielberger Trait Anxiety Scale 5. Expanded Disability Status Scale 6. 25-foot walk test Timepoints of assessment: pre-Intervention, post-intervention and 6-month post-intervention.
Disability progressionThinking and memoryWalking and mobilityMood and sleepQuality of life (reported by participants)
Who could take part
Relapsing and progressive · 18 and over
Show the full criteria
Inclusion criteria
Inclusion: 1. Both males and females, aged 18 - 70 years 2. Verified diagnosis of MS with an expanded disability status scale score of less than or equal to 6.0 (from no disability to moderately severe disability MS) and no more than one step increase within the last year. We include patients with the followng types of disease: 2.1. Relapsing-remitting MS and no more than two exacerbations within the last year, with at least three months since start of last relapse; or 2.2. Secondary progressive disease 3. Patients who have not initiated or changed treatment with a disease-modifying drug within the past three months 4. Patients who have not been treated with corticosteroids within the previous 30 days 5. Time since onset of disease will be evaluated and considered in statistical analyses but will not form a criterion for enrolment into the study Exclusion: 1. Serious psychological disorders other than depression and anxiety syndromes, such as psychotic disorders, bipolar disorders, borderline personality disorders or active substance abuse disorders 2. Evidence of dementia as indicated by testing below the fifth percentile in at least three of six dimensions of neuropsychological functioning (i.e. attention and concentration, processing speed, executive function, verbal memory, and verbal processing) 3. Suicidality 4. Other life-threatening or severely disabling physical disorders 5. Current MS exacerbation 6. Other disorders of the central nervous system (CNS) besides MS 7. Symptomatic medication has been altered within the past three months 8. Pregnancy 9. Inability to understand written and spoken German
Exclusion criteria
Not separately supplied in the registry.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Not provided at time of registration
Papers
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History
Started
Apr 2007
Finished
Jun 2009