Randomised placebo-controlled trial of intravenous methylprednisolone
Randomised placebo-controlled trial of intravenous methylprednisolone in relapsed multiple sclerosis patients without the need for ranitidine cover
What it found
We found no results in the registry or in papers.
This trial finished 21 years ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- Methylprednisolone
Glucocorticoid receptor agonist
- Ranitidine
Histamine H2 receptor antagonist
What it measured
Main measures
Between group differences in the absolute number of those who develop gastro-intestinal symptoms.
Other measures (1)
The number of those who develop gastro-intestinal symptoms who on clinical grounds require further investigation of their gastric mucosa for a possible ulcer or erosions in the 3, 6 and 12 months follow up durations.
Who could take part
MS (type not specified)
Show the full criteria
Inclusion criteria
Inclusion: Sixty matched patients from those admitted for intravenous methylprednisolone treatment for their relapsed multiple sclerosis. Exclusion: Not provided at time of registration
Exclusion criteria
Not separately supplied in the registry.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Not provided at time of registration
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History
Started
Jul 2003
Finished
Nov 2004