Teleconference Fatigue Management for People With Multiple Sclerosis
Effectiveness of a Teleconference Delivered Fatigue Management Program for People With Multiple Sclerosis
What it found
The main measure showed a statistically significant benefit.
| Measure | Estimate | 95% CI | p |
|---|---|---|---|
| Change From Baseline in Subscale Scores of the Fatigue Impact Scale | Mean Difference (Net) -2.53 | -15.47–10.41 | <0.05 |
Statistical analysis as posted on ClinicalTrials.gov.
What was tested
Treatment tested
- Energy conservation education
Results by group
Change From Baseline in Subscale Scores of the Fatigue Impact Scale
baseline, 7 weeks (immediate post-intervention)
| Group | Value | Interval | Number analysed |
|---|---|---|---|
| Immediate Group | -3.74 units on a scale | 6.74 (Standard Deviation) | 89 |
| Wait List | -1.22 units on a scale | 6.24 (Standard Deviation) | 92 |
| Immediate Group | -4.24 units on a scale | 6.01 (Standard Deviation) | 89 |
| Wait List | -1.11 units on a scale | 6.18 (Standard Deviation) | 92 |
| Immediate Group | -8.39 units on a scale | 11.66 (Standard Deviation) | 89 |
| Wait List | -2.38 units on a scale | 12.4 (Standard Deviation) | 92 |
p = <0.05; Mean Difference (Net) -2.53 (95% CI -15.47–10.41)
Values as posted on ClinicalTrials.gov. Outcomes measured differently across trials are not directly comparable.
Safety
| Group | Participants at risk | Serious adverse events | Deaths |
|---|---|---|---|
| Immediate Group | 89 | 0 (0.0%) | |
| Wait List | 92 | 0 (0.0%) |
As posted on ClinicalTrials.gov. Serious adverse events include any serious health event during the trial, whether or not the treatment caused it.
What it measured
Main measures
Change From Baseline in Subscale Scores of the Fatigue Impact Scale
baseline, 7 weeks (immediate post-intervention)
Thinking and memoryFatigue
Who could take part
MS (type not specified) · 18 and over
Show the full criteria
Inclusion criteria
* a diagnosis of MS * 18 years of age or older * functional English literacy (i.e., able to read course materials and carry on telephone conservations in English) * Fatigue Severity Scale score of 4 or greater * Residing in the state of Illinois
Exclusion criteria
* Short version - Blessed Orientation Memory Concentration Test - outside of normal range
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Approximately 60% of individuals with multiple sclerosis (MS) describe fatigue as their most disabling symptom. Energy conservation education involves teaching people with MS different strategies to manage fatigue and reduce its impact on daily life. Despite growing evidence of the effectiveness of face-to-face energy conservation education, not all people with MS are able to access these programs. The purpose of this project is to test the effectiveness and efficacy of a teleconference-delivered energy conservation education program for people with MS. The primary goals of the project are to reduce the impact of fatigue on participants' everyday lives, reduce fatigue severity, and improve quality of life. Secondary goals are to increase self-efficacy for managing fatigue and increase the number of energy conservation strategies used. The study will employ a randomly allocated two group time series design with a wait-list control group, which is one type of randomized control trial. A total of 181 people with MS will be recruited through direct mailing and advertising. The program will be delivered by telephone teleconference by a licensed occupational therapist. Outcome measures will be administered over the telephone by a research assistant before and after the program, at three months and at six months. We hypothesize that: (1) individuals in the immediate intervention group achieve better outcomes than individuals in the wait-list control group; (2) the program leads to significant reductions in fatigue impact and fatigue severity, and improved quality of life; and (3) improvements in the outcomes can be maintained over six months.
Papers
Results
Finlayson M, Preissner K, Cho C, Plow M. Randomized trial of a teleconference-delivered fatigue management program for people with multiple sclerosis. Mult Scler. 2011 Sep;17(9):1130-40. doi: 10.1177/1352458511404272. Epub 2011 May 11.Results
Finlayson M, Preissner K, Cho C. Outcome moderators of a fatigue management program for people with multiple sclerosis. Am J Occup Ther. 2012 Mar-Apr;66(2):187-97. doi: 10.5014/ajot.2012.003160.
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History
Started
Nov 2007
Main results due
Feb 2010
Finished
Feb 2010
Results posted
Feb 2013