Mindfulness Based Stress Reduction in Multiple Sclerosis (MS)
Mindfulness Based Stress Reduction in MS
What it found
We found no results in the registry or in papers.
This trial finished 13 years ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- Mindfulness based stress reduction (MBSR)
What it measured
Main measures
Electronic measure of needle disposals (MEMS TrackCaps)
Medication adherence will be measured by total number of missed doses, calculated from total needle disposals. The total number of missed doses across the six weeks will be compared between the two tr
Quality of life (reported by participants)
Other measures (10)
Perceived Stress Scale-10
Baseline, 1 X between weeks 3-7, Week 8
Holmes and Rahe Social Readjustment Rating Scale (SRRS
Baseline, 1 X between weeks 3-7, Week 8
Bladder, bowel and sexual functionChicago Multiscale Depression Inventory (CMDI)
Baseline, 1 X betweeen Weeks 3-7, Week 8
Mood and sleepState Trait Anxiety Inventory (STAI)
Baseline, 1 X betweeen Weeks 3-7, Week 8
Mood and sleepPositive and Negative Affect Scale (PANAS)
Baseline, 1 X between Weeks 3 - 7, Week 8
Fatigue Severity Scale (FSS)
Baseline, 1 X between Weeks 3 - 7, Week 8
FatigueMACFIMS neuropsychological battery
Baseline and Week 8
Disability progressionThinking and memoryExpanded Disability Status Scale (EDSS)
Baseline and Week 8
Disability progressionPhysiologic Markers of Stress
Baseline and Week 8
Physiologic Maker of Stress
Baseline, 1 X between Week 3 - 7, Weeek 8
Who could take part
Early (CIS/RIS) · 18 to 70
Show the full criteria
Inclusion criteria
* Patients with either definite MS according to the revised McDonald criteria (Polman 2005) or patients with CIS (defined as an initial MS relapse with objective documentation and 2 or more lesions within the CNS of which at least one must involve the brain) * Patients on GA therapy for at least 6 months * Age 18 - 70
Exclusion criteria
* Unwilling to comply with study procedures * Use of other DMT in conjunction with GA * Unable to provide informed consent. * Current (past 30 days) substance abuse * Newly initiated (past 30 days) psychiatry treatment * Enrolled in another program of meditation in the past six months.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
This study focuses on stress, cognition, mood and fatigue and its effect on medication compliance. Medication compliance is measured by the weight of discarded needles. The investigators will be administering neuropsychological testing at baseline and the final visit. The subjects will complete self-report assessments during their 8 weeks in the study. Group A will have additional weekly phone support for meditation, while Group B will have meditation training only.
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History
Started
May 2011
Main results due
Apr 2013
Finished
Nov 2014