Apraxia-specific Occupational Therapy in Patients With Multiple Sclerosis

CompletedNot a drug-phase studyMS (type not specified)NCT01507636

What it found

Paper found, not read

A paper reports the results; we have not read it yet. See Papers below.

What was tested

Treatment tested

  • Occupational Therapy
  • Physical therapy

What it measured

Main measures

  • Change in apraxia score as measured by TULIA

    From day of randomisation to end of study, expected to be after 4 weeks

Other measures (4)

  • Change in manual dexterity

    From day of randomisation to end of study, expected to be after 4 weeks

    Arm and hand function
  • Change in activities of daily living

    From day of randomisation to end of study, expected to be after 4 weeks

  • Change in quality of life

    From day of randomisation to end of study, expected to be after 4 weeks

    Quality of life (reported by participants)
  • Change in fatigue

    From day of randomisation to end of study, expected to be after 4 weeks

    Fatigue

Who could take part

MS (type not specified) · 18 to 60

Show the full criteria

Inclusion criteria

* Patients with all forms of MS * Age 18-60 years

Exclusion criteria

* Any disease other than multiple sclerosis that could possibly explain the patient's signs and symptoms * A relapse which started within 60 days prior to the examination * Uncontrolled, clinically significant heart diseases, such as arrhythmias, angina, Coronary heart disease or uncompensated congestive heart failure, medication with glycosides. * A history of drug abuse in the 6 months prior to screening

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Limb apraxia is defined as the inability to correctly perform skilled and/or learned limb movements, which cannot be explained by elementary motor and sensory deficits or cognitive problems. Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system and the leading cause of disability in young adults. Apraxia and impaired manual dexterity are common problems in patients with MS leading to impaired activities of daily living. However, a specific training program to improve apraxia as well as manual dexterity in MS is lacking. In this study, the investigators want to evaluate the impact of a targeted occupational therapy program on apraxia and manual dexterity in patients with MS that have dexterity problems. Patients routinely seen in the investigators MS consulting hour, fulfilling all inclusion and exclusion criteria and willing to participate in the study will be evaluated for Apraxia and manual dexterity. In case of Apraxia and/or impaired manual dexterity, patients will be randomized 1:1 using sealed envelopes to receive occupational home therapy (experimental group) or general physical exercises (control group) for 4 weeks. At study entry and study end after 4 weeks, apraxia and manual dexterity will be tested in all patients.

Papers

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History

    1. Started

      Jan 2012

    2. Main results due

      Dec 2012

    3. Finished

      Dec 2012

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