Impact of Vitamin A on RAR Gene Expression in Multiple Sclerosis
Impact of Vitamin A Supplementation on RAR Gene Expression in PBMC Cells in Multiple Sclerotic Patients
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- Vitamin a palmitate
Placebo
- placebo
What it measured
Main measures
Gene expression of RAR(Relative quantification)
Change from baseline at 6 months
Immune response
Who could take part
Relapsing MS · 20 to 45
Show the full criteria
Inclusion criteria
* Patients who have used interferon beta in last 3 months. * Patients with 0-5 EDSS
Exclusion criteria
* Patients who have diseases which affect on Th1/Th2 balance such as asthma, active viral infections, and autoimmune diseases, OR * Patients who have allergy to vitamin A compounds, OR * Patients who have used vitamin supplements in last 3 months.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The aim of this study is the comparison between the effects of supplementation with 25000 IU preformed vitamin A (retinyl palmitate)on retinoic acid receptor and retinoic x receptor expression.
Papers
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History
Started
Feb 2010
Main results due
Feb 2013
Finished
Aug 2013