Rehabilitation in Multiple Sclerosis: Influence of Exercise on Develop

Rehabilitation in Multiple Sclerosis: Influence of Exercise on Development of Insulin Resistance, Muscle Power and Aerobic Capacity

CompletedNot a drug-phase studyMS (type not specified)NCT01718392

What it found

Paper found, not read

A paper reports the results; we have not read it yet. See Papers below.

What was tested

Treatment tested

  • Training

What it measured

Main measures

  • insulin sensitivity (insulin profile)

    change from baseline to 24 weeks

Other measures (10)

  • aerobic capacity

    change from baseline to 24 weeks

    Physical function

  • aerobic capacity - lactate concentrations

    change from baseline to 24 weeks

    Physical function

  • cytokine profile

    change from baseline to 24 weeks

    Immune response

  • walking performance

    change from baseline to 24 weeks

    Walking and mobility

  • Self-reported measures

    Change from baseline to 24 weeks

  • body composition

    Change from baseline to 24 weeks

    Physical function

  • muscle strength of knee flexor

    change from baseline to 24 weeks

    Physical function

  • muscle strength of knee extensor

    change from baseline to 24 weeks

    Physical function

  • muscle strength of elbow flexor

    change from baseline to 24 weeks

    Physical function

  • muscle strength of elbow extensor

    change from baseline to 24 weeks

    Physical function

Who could take part

MS (type not specified) · 18 to 65 · EDSS 0.5 to 6

Show the full criteria

Inclusion criteria

* Diagnosed MS according to the McDonald criteria * Expanded Disability Status Scale (EDSS) between 0.5 and 6 * Be able to train 5 times in 2 weeks at the University

Exclusion criteria

* Comorbidities like cardiovascular-, respiratory-, orthopaedic or metabolic diseases (like diabetes type 2) * Having had an relapse in a period of 3 months prior to the start of the intervention period * Having an relapse during the intervention period * Pregnancy and other contra indications for physical activity * Mental disorders

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

the purpose of this study is to investigate the development of insulin resistance in multiple sclerosis patients + explaining the effects of a combined training programme on insulin resistance, muscle power and aerobic capacity in multiple sclerosis patients

Papers

Loading reviews and guidelines…

History

    1. Started

      Mar 2011

    2. Main results due

      Mar 2013

    3. Finished

      Sept 2013

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