The Effect of Aerobic Exercise on Cognitive Function and Sleep Quality
The Effect of Aerobic Exercise on Cognitive Function and Sleep Quality in Individuals With Multiple Sclerosis
What it found
We found no results in the registry or in papers.
This trial finished 10 years ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- aerobic exercise
Compared with
- home exercise program
What it measured
Main measures
Change in Cognitive Function
Baseline to Month 3
Thinking and memory
Other measures (1)
Change in Sleep Quality
Baseline to Month 3
Mood and sleep
Who could take part
Relapsing and progressive · 21 to 80
Show the full criteria
Inclusion criteria
* diagnosis of relapsing remitting or secondary progressive MS * score 3-7 on the EDSS * score \< 55 on the Symbol Digit Modalities Test * score > 5 on the Pittsburgh Sleep Quality Index
Exclusion criteria
* history of alcohol/drug abuse or nervous system disorder other than MS * severe physical, neurological, or sensory impairments that would interfere significantly with testing * developmental history of learning disability or attention-deficit/hyperactivity disorder * relapse and/or corticosteroid use within four weeks of assessment * unable to give consent * uncorrected vision loss that would interfere significantly with testing * score less than 24 on MMSE * Acute ischemic cardiovascular event or coronary artery bypass surgery less than 3 months ago * Either unable to physically perform the exercise test using the recumbent stepper or demonstrate absolute indications for terminating exercise that follows the American College of Sports Medicine's (ACSM) guidelines * Uncontrolled blood pressure with medication (BP > 190/110mmHg)
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
In addition to the typical motor and sensory impairments, individuals with multiple sclerosis (MS) often experience cognitive dysfunction and sleep disturbances. Cognitive impairment occurs in 40 % - 70% of patients with MS. In addition, sleep problems in individuals with MS are very common, and approximately 50% of patients with MS have a diagnosable sleep disorder. The research believes that aerobic exercise improve cognitive function and improve sleep quality.
Papers
Loading reviews and guidelines…
History
Started
Aug 2012
Main results due
Dec 2015
Finished
Dec 2015