Exercise, Subclinical Atherosclerosis and Walking Mobility in Multiple Sclerosis

CompletedNot a drug-phase studyMS (type not specified)NCT01824550

What it found

No results found

We found no results in the registry or in papers.

This trial finished 9 years ago. We found no results in the registry or in any paper that cites it.

What was tested

Treatment tested

  • home-based exercise training condition

What it measured

Main measures

  • Subclinical atherosclerosis

    3 months

Other measures (1)

  • Mobility disability

    3 months

    Walking and mobility

Who could take part

MS (type not specified) · 18 to 70 · EDSS 0 to 4.0

Show the full criteria

Inclusion criteria

* physically inactive * BMI\<40 * 1st stage of MS (i.e., defined as EDSS score of 0 - 4.0) * independently ambulatory (walking without an assistive device such as a cane or orthotic) * relapse free in the past 30 days * confirmed diagnosis of MS * asymptomatic (i.e., no underlying clinically diagnosed cardiovascular disease) * be on a stable disease modifying therapy * physician approval for undertaking exercise testing and training

Exclusion criteria

Not separately supplied in the registry.

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

The objective of this study is to determine the effect of home-based, aerobic exercise training on subclinical atherosclerosis and mobility disability in persons with Multiple Sclerosis (MS). Our central hypothesis is that aerobic exercise training reduces both subclinical atherosclerosis and mobility disability.

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History

    1. Started

      Nov 2012

    2. Main results due

      Sept 2017

    3. Finished

      Sept 2018

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