Lung Volume Recruitment for Lung Function and Cough Impairment in Mult
Lung Volume Recruitment for Lung Function and Cough Impairment in Multiple Sclerosis
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- Lung volume recruitment
What it measured
Main measures
Rate of decline of FVC (forced vital capacity)
up to 9 months
Other measures (3)
Rate of decline of peak cough flow
baseline, 2, 4, 6 and 9 months
Change from baseline in FVC at 2, 4, 6 and 9 months
baseline vs 2, 4, 6 and 9 months
Change from baseline in peak cough flow at 2, 4, 6 and 9 months
baseline vs 2, 4, 6 and 9 months
Who could take part
MS (type not specified) · 18 and over
Show the full criteria
Inclusion criteria
* History of multiple sclerosis, diagnosed by a neurologist in accordance with the 2010 McDonald criteria
Exclusion criteria
* Concomitant parenchymal pulmonary disease or pleural disease * Symptomatic cardiomyopathy * Unable to perform pulmonary function testing or lung volume recruitment, due to comprehension or cooperation issues, physical inability such as bulbar or cerebellar dysfunction * Contra-indication to pulmonary function testing or lung volume recruitment such as myocardial infarction, bleeding aortic aneurysm, intracranial hemorrhage within the previous month * Known susceptibility to pneumothorax or pneumomediastinum * Not competent to provide informed consent
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Multiple sclerosis is a neurological disease that can affect lung function and cough efficacy. This pilot study will examine whether the lung volume recruitment technique can slow down the decline in lung function and cough.
Papers
Loading reviews and guidelines…
History
Started
Jul 2013
Main results due
Apr 2017
Finished
Apr 2017