Analgesic Effect of Repetitive Transcranial Magnetic Stimulation (rTMS
Analgesic Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) for Central Neuropathic Pain in Multiple Sclerosis
We could not find results for this trial
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- Repetitive Transcranial Magnetic Stimulation (rTMS)
What it measured
Main measures
Change from baseline in "average pain" score on the brief pain inventory
at day 8
Pain
Other measures (5)
change from baseline in "average pain" score on the brief pain inventory
at weekk 3 and 4
PainLocation of MRI abnormalities
at week 3 and 4
MRI lesionsPainIntra-cortical excitability evaluated by motor threshold, MEP amplitude, SICI and ICF
at week 3 and 4
Nerve conduction testsNumber of participants with adverse events as a measure of safety and tolerability
at day 1
Safetychange from baseline in specific questionnaires
at day 8, week 3 and 4
Who could take part
Relapsing MS · 18 to 60
Show the full criteria
Inclusion criteria
* relapsing-remitting Multiple Sclerosis * 18 to 60 years * central neuropathic pain with a DN4 score of 4 or more out of 10 * average pain of at least 4/10 * presence of pain at least 4 days per week * presence of pain for at least 3 months * stable analgesic treatment
Exclusion criteria
* relapse during the previous 30 days * contraindication for rTMS * peripheral neuropathic pain * severe depression * epilepsia * resting motor threshold above 75%
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
This study is designed to evaluate the effect of repetitive Transcranial Magnetic Stimulation (rTMS) in the resolution of chronic pain. Participants will be patients with Multiple Sclerosis suffering from chronic pain of neurological origin.
Papers
Loading reviews and guidelines…
History
Started
Jan 2014
Main results due
Feb 2023
Finished
Feb 2023