EMISEP : Early Spinal Cord Lesions and Late Disability in Relapsing Re
EMISEP : Early Spinal Cord Lesions and Late Disability in Relapsing Remitting Multiple Sclerosis Patients
What it found
A paper reports the results; we have not read it yet. See Papers below.
What was tested
Treatment tested
- spinal cord MRI follow-up
- clinical follow-up
- brain MRI follow-up
What it measured
Main measures
Progressive neurological disability
5 years
Other measures (4)
Progressive ambulatory disability
5 years
Walking and mobilityProgressive disability in the upper limbs
5 years
Arm and hand functionProgressive urinary disability
5 years
Bladder, bowel and sexual functionProgressive difficulty walking
5 years
Walking and mobility
Who could take part
Relapsing MS · 18 to 40
Show the full criteria
Inclusion criteria
Patients with multiple sclerosis: Inclusion Criteria: * Relapsing Remitting Multiple Sclerosis patients (Mac Donald 2010 criteria) * First clinical event \< 1 year * Brain MRI > 9 lesions or/and spinal cord attack with focal lesion on spinal cord MRI * Score Expended Disability Status Scale \< 3 * Age between 18 and 40 years
Exclusion criteria
* Multiple Sclerosis progressive * Patients treated with immunosuppressive therapy * Pregnancy Healthy volunteers: Inclusion Criteria: -Age between 18 and 40 years Exclusion Criteria: -Pregnancy
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The purpose of this study is to evaluate the prognostic value of early focal lesions and early diffuse lesions on ambulatory disability progression within 5 years after clinical onset.
Papers
Loading reviews and guidelines…
History
Started
Jan 2014
Main results due
Jan 2023
Finished
Jan 2024