Treating Foot Drop in People With Multiple Sclerosis Using Electrical
Functional Electrical Stimulation to Treat Foot Drop in People With Multiple Sclerosis
What it found
We found no results in the registry or in papers.
This trial finished 10 years ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- Bioness L300 Foot Drop System
What it measured
Main measures
Speed during the 10-metre straight line walking test
12 weeks
Walking and mobility
Other measures (10)
Distance travelled during the 4-minute figure-8 walking test
12 weeks
Walking and mobilitySpeed during the 10-metre straight line walking test
4 weeks
Walking and mobilitySpeed during the 10-metre straight line walking test
8 weeks
Walking and mobilityDistance travelled during the 4-minute figure-8 walking test
4 weeks
Walking and mobilityDistance travelled during the 4-minute figure-8 walking test
8 weeks
Walking and mobilityPhysiological cost index during walking tests
4 weeks
Walking and mobilityPhysiological cost index during walking tests
8 weeks
Walking and mobilityPhysiological cost index during walking tests
12 weeks
Walking and mobilityParticipant satisfaction questionnaire score
12 weeks
Quality of life (reported by participants)Treadmill Gait Assessment
12 weeks
Walking and mobility
Who could take part
MS (type not specified) · 18 and over
Show the full criteria
Inclusion criteria
* Have multiple sclerosis for at least one year * Being 18 years of age or older * Have upper motor neuron-type foot drop (based on the study clinician's medical opinion) * Able to ambulate at least 10 metres independently or with one person assistance, with or without walking aid * Having the cognitive capacity to understand and follow the study protocol
Exclusion criteria
* Severe cardio-respiratory difficulties (including using a pace-maker) or other health issues that may prohibit walking training * Significant lower motor neuron neuropathy (based on the study clinician's medical opinion) * History of frequent falls (more than once a week) * Having used functional electrical stimulation to treat gait within the past six months
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
People with multiple sclerosis (MS) often suffer from foot drop, which impairs their walking ability. Foot drop is the inability to lift the foot during the swing phase of walking. The purpose of this study is to find out if electrical stimulation of the leg, using the Bioness L300 Foot Drop System, can be used to treat foot drop in people with MS. It is expected that using this system will reduce foot drop, and therefore improve walking ability, particularly in the areas of speed, strength, balance and falls.
Papers
Background
Laufer Y, Hausdorff JM, Ring H. Effects of a foot drop neuroprosthesis on functional abilities, social participation, and gait velocity. Am J Phys Med Rehabil. 2009 Jan;88(1):14-20. doi: 10.1097/PHM.0b013e3181911246.Background
Ring H, Treger I, Gruendlinger L, Hausdorff JM. Neuroprosthesis for footdrop compared with an ankle-foot orthosis: effects on postural control during walking. J Stroke Cerebrovasc Dis. 2009 Jan;18(1):41-7. doi: 10.1016/j.jstrokecerebrovasdis.2008.08.006.Background
Stein RB, Everaert DG, Thompson AK, Chong SL, Whittaker M, Robertson J, Kuether G. Long-term therapeutic and orthotic effects of a foot drop stimulator on walking performance in progressive and nonprogressive neurological disorders. Neurorehabil Neural Repair. 2010 Feb;24(2):152-67. doi: 10.1177/1545968309347681. Epub 2009 Oct 21.Background
O'Dell MW, Dunning K, Kluding P, Wu SS, Feld J, Ginosian J, McBride K. Response and prediction of improvement in gait speed from functional electrical stimulation in persons with poststroke drop foot. PM R. 2014 Jul;6(7):587-601; quiz 601. doi: 10.1016/j.pmrj.2014.01.001. Epub 2014 Jan 9.
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History
Started
Jun 2014
Main results due
Jul 2016
Finished
Jul 2016