Computerized Exercise Training for Cognitive Remediation in Adults Wit
A Pilot Study of Plasticity-Based and Adaptive Cognitive Remediation in Adults With Multiple Sclerosis Treated With Gilenya
What it found
We found no results in the registry or in papers.
This trial finished 12 years ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- plasticity-based computerized cognitive remediation program
Given to everyone in the trial
- Gileyna
What it measured
Main measures
Change from Baseline in Neuropsychological Test Results at 12weeks
12 weeks
Other measures (1)
Evaluate the feasibility of PACR for adults with MS on Gilenya therapy who have cognitive impairment based on Participant Adherence to Study Protocol
12 weeks
Thinking and memoryQuality of life (reported by participants)Feasibility
Who could take part
Relapsing MS · 18 to 70
Show the full criteria
Inclusion criteria
* Ages 18-70 * Relapsing Remitting MS Diagnosis [81] * Initiating Gilenya therapy, or current Gilenya therapy (kept constant for the past one month) * No relapse or steroids in previous month * Reading score on WRAT-3 of 37 or greater * Visual, auditory and motor capacity to operate computer software, as judged by treating neurologist or study staff.
Exclusion criteria
* Previous trial of Gilenya therapy * History of mental retardation, pervasive developmental disorder or other neurological condition associated with cognitive impairment * Primary psychiatric disorder or unstable medical disorder that would influence ability to participate * History of computer-based training with procedures similar to those proposed * Learned English language after 12 years of age * Unable to comply with study procedures
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
This study is investigating the efficacy of computer-based cognitive exercises as a means of cognitive remediation in patients with Multiple Sclerosis (MS) who are beginning the disease modifying pharmacotherapy Gileyna.
Papers
Loading reviews and guidelines…
History
Started
Aug 2013
Main results due
Sept 2014
Finished
Sept 2015