Psychometric Properties Mobility Measures MS
Psychometric Properties of Mobility, Beyond Walking Speed, in Multiple Sclerosis: a Multi-center Study.
What it found
We found no results in the registry or in papers.
This trial finished 10 years ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- conventional MS rehabilitation
What it measured
Main measures
Timed 25-Foot Walk test (T25FW)
day 1 and at the end of the rehabilitation, an expected average of three months
Disability progressionWalking and mobilityTimed up and go (TUG), TUGcognitive
day 1 and at the end of the rehabilitation, an expected average of three months
Thinking and memoryWalking and mobilityTwo minute walk test (2MWT)
day 1 and at the end of the rehabilitation, an expected average of three months
Walking and mobilityFour Square Step Test (FSST)
day 1 and at the end of the rehabilitation, an expected average of three months
5 repetition sit-to-stand test (5STS-test)
day 1 and at the end of the rehabilitation, an expected average of three months
Modified 5 repetition sit-to-stand test (mod 5STS-test)
day 1 and at the end of the rehabilitation, an expected average of three months
Rivermead Mobility Index (RMI)
day 1 and at the end of the rehabilitation, an expected average of three months
Walking and mobilityMultiple Sclerosis Walking Scale-12 (MSWS-12)
day 1 and at the end of the rehabilitation, an expected average of three months
Walking and mobilityPerformance Scale mobility (PS-mob)
day 1 and at the end of the rehabilitation, an expected average of three months
Walking and mobility
Other measures (6)
Timed Up and Go, manual
day 1 and at the end of the rehabilitation, an expected average of three months
Walking and mobilityBerg Balance Scale (BBS)
day 1 and at the end of the rehabilitation, an expected average of three months
Walking and mobilityDynamic Gait index (DGI)
day 1 and at the end of the rehabilitation, an expected average of three months
Walking and mobilityActivities-specific Balance Confidence Scale (ABC)
day 1 and at the end of the rehabilitation, an expected average of three months
Walking and mobilityTrunk Impairment Scale, modified Norwegian version (TIS-modNV)
day 1 and at the end of the rehabilitation, an expected average of three months
International Physical Activity Questionnaire (IPAQ)
day 1 and at the end of the rehabilitation, an expected average of three months
Physical function
Who could take part
MS (type not specified) · 18 and over
Show the full criteria
Inclusion criteria
* Diagnosis of MS according to McDonald criteria24, * Expanded Disability Status Scale25 (EDSS) ≥ 2 and ≤ 6.5 as determined by neurologists or trained clinician * no relapse within the last month * no changes in disease modifying treatment and no corticoid-therapy within the last month * receive at least 10 sessions of physical therapy (in- or outpatient rehabilitation), with a maximum duration of 3 months
Exclusion criteria
* other medical conditions interfering with mobility (e.g. stroke, pregnancy, fractures, …) * other neurological impairments with permanent damage (stroke, Parkinson, …) * MS-like syndromes such as neuromyelitis optica * not able to understand and execute simple instructions
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Current study will investigate the quality (psychometric properties) and clinical utility of several mobility measures, according to disability level. Therefore, several aspects will be inquired: * Was there an effect of rehabilitation * Is the measure able to detect change over time? And thus the change exceed measurement error and is it clinically important (responsiveness) * Does the measure assess what it claims to measure (validity) * Is the measure able to differentiate all performances of the patients, inclusively the very good and very bad performances (floor and ceiling effects) * Does the measure gives similar results under consistent test conditions on another testing day (reliability) Worldwide, theoretical approaches to physical therapy and rehabilitation in Multiple Sclerosis often appear significantly different. Since the present research protocol will be performed at different centers across European countries (and US sites), this multi-center study can additionally be applied for mapping the volume and content of rehabilitation, as well as the differential impact of diverse rehabilitation approaches and training volume on mobility, for several disability levels. Some health-economic analyses will be performed to examine what the approximate cost of rehabilitation compared to effects is and what drivers of costs are (setting, equipment, staff).
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History
Started
Oct 2014
Main results due
Dec 2015
Finished
Jun 2016