Profile of Adherence to Therapy and Interventions to Promote Adherence
Personal Profile of Adherence to Therapy and Tailored Interventions to Promote Adherence in Multiple Sclerosis Patients
What it found
A paper reports the results; we have not read it yet. See Papers below.
What was tested
Treatment tested
- Behavioral Intervention
What it measured
Main measures
Adherence to therapy by assessment of remaining pills/medication claims electronic records
24 months
Quality of life (reported by participants)Adherence to therapy according to ProMas
24 months
Quality of life (reported by participants)Adherence to therapy according to MS-TAQ
24 months
Quality of life (reported by participants)
Other measures (1)
Improvement in quality of life
24 months
Quality of life (reported by participants)
Who could take part
MS (type not specified) · 18 to 70
Show the full criteria
Inclusion criteria
* MS patients according to Poser diagnosis * treated or planned to be treated with Disease Modifying Therapies * age 18 to 70 * signed informed consent * both male and female
Exclusion criteria
* pregnant women
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Adherence is an active process wherein the patient acts in collaboration with the medical and paramedical staff in order to improve his/her health. Adherence to medication comprises of implementation and persistence and it is estimated to be around 50% in various chronic illnesses, including Multiple Sclerosis (MS). MS patients who fail to properly adhere to their DMTs regimen may be at increased risk for the development of new central nervous system lesions, exacerbations, increased disabilities and poorer quality of life. Plausible reasons for the low adherence rates in MS mentioned in the literature include patients' attributes, condition attributes and therapy related factors. The objective of this study is to develop a personal profile of adherence based in the factors mentioned above. In the first part of the study patients will be followed up and the profile My Multiple Sclerosis Perception Adherence Scoring System (MyMS_PASS) will be created and tested. In the second part, patients with non-optimal rates of adherence will receive tailored intervention in order to improve therapy to treatment. This work may serve as a model for the study of adherence to therapy and the development of interventions in MS as well as in other chronic diseases.
Papers
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History
Started
Aug 2015
Main results due
Jun 2024
Finished
Jun 2024