Personal Profile of Adherence to Therapy and Tailored Interventions to Promote Adherence in Multiple Sclerosis Patients

Status unknownNot a drug-phase studyMS (type not specified)NCT02488343

What it found

Paper found, not read

A paper reports the results; we have not read it yet. See Papers below.

What was tested

Treatment tested

  • Behavioral Intervention

What it measured

Main measures

  • Adherence to therapy by assessment of remaining pills/medication claims electronic records

    24 months

    Quality of life (reported by participants)
  • Adherence to therapy according to ProMas

    24 months

    Quality of life (reported by participants)
  • Adherence to therapy according to MS-TAQ

    24 months

    Quality of life (reported by participants)

Other measures (1)

  • Improvement in quality of life

    24 months

    Quality of life (reported by participants)

Who could take part

MS (type not specified) · 18 to 70

Show the full criteria

Inclusion criteria

* MS patients according to Poser diagnosis * treated or planned to be treated with Disease Modifying Therapies * age 18 to 70 * signed informed consent * both male and female

Exclusion criteria

* pregnant women

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Adherence is an active process wherein the patient acts in collaboration with the medical and paramedical staff in order to improve his/her health. Adherence to medication comprises of implementation and persistence and it is estimated to be around 50% in various chronic illnesses, including Multiple Sclerosis (MS). MS patients who fail to properly adhere to their DMTs regimen may be at increased risk for the development of new central nervous system lesions, exacerbations, increased disabilities and poorer quality of life. Plausible reasons for the low adherence rates in MS mentioned in the literature include patients' attributes, condition attributes and therapy related factors. The objective of this study is to develop a personal profile of adherence based in the factors mentioned above. In the first part of the study patients will be followed up and the profile My Multiple Sclerosis Perception Adherence Scoring System (MyMS_PASS) will be created and tested. In the second part, patients with non-optimal rates of adherence will receive tailored intervention in order to improve therapy to treatment. This work may serve as a model for the study of adherence to therapy and the development of interventions in MS as well as in other chronic diseases.

Papers

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History

    1. Started

      Aug 2015

    2. Main results due

      Jun 2024

    3. Finished

      Jun 2024

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