Influence of Emotional Disorders and Executive on the Components Retro
Influence of Emotional Disorders and Executive on the Components Retrograde and Anterograde Episodic Memory in MS
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- Neuropsychological tests
What it measured
Main measures
anterograde episodic memory: 3 scores of emotional ESR
baseline
Thinking and memoryretrograde episodic memory: 9 scores TEMP emotional
baseline
Thinking and memory
Who could take part
Relapsing and progressive · 30 to 60
Show the full criteria
Inclusion criteria
* Men and women 30-60 years of age * Definite MS (McDonald criteria revised in 2005) * EDSS \<6 * Sick Shapes: Relapsing multiple sclerosis, Primary progressive multiple sclerosis * All durations evolution * French Mother tongue * Signature of informed consent
Exclusion criteria
* Other neurological conditions, previous psychiatric or developmental diagnosis of MS * Head injury sequelae * Chronic alcohol or drugs Taking * EDSS greater than or equal to 6 * Secondary Progressive Form * Push and / or treatment with corticosteroids within one month * Treatments Amantadine, Modafinil introduced for less than 3 months * Patient Trust * Cognitive Assessment of less than one year (including in particular all or part of the balance sheet proposed in this project) * Any visual motor deficit or incompatible with the award of cognitive tests * For women, pregnancy, breastfeeding and / or lack of contraception (a pregnancy test will be done before the PET scan) * Patient with indications against MRI
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system responsible for physical disability but can also cause cognitive disturbances annoying social and professional life of patients with the disease. Various studies have shown that there was a breach of episodic memory, working memory, attention and executive functions regardless of the form of disease, disability or duration of disease progression. The main objective of this study is to investigate the influence of emotional components and executive processes on the components retrograde and anterograde episodic memory (thanks to an original paradigm based on the emotional valence of the memory) in MS patients
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History
Started
Jun 2010
Main results due
Jul 2016