Influence of Exercise on the Mobility and Balance of Individuals With Multiple Sclerosis Influence of High-Dosage Physical Therapy on the Balance and Mobility of Individuals With Multiple Sclerosis

CompletedNot a drug-phase studyMS (type not specified)NCT02524483

What it found

Paper found, not read

A paper reports the results; we have not read it yet. See Papers below.

What was tested

Treatment tested

  • Therapeutic Challenge Program

Compared with

  • Therapeutic Exercise Program

What it measured

Main measures

  • Changes in Balance Using the Sensory Organization Test

    Baseline and 6 weeks

    Walking and mobility
  • Changes in Walking Velocity, Step Lengths, Step Widths, and Cadence

    Baseline and 6 weeks

    Walking and mobility

Other measures (1)

  • Changes in Endurance using the 6-Minute Walk

    Baseline and 6 weeks

    Walking and mobility

Who could take part

MS (type not specified) · 30 to 70

Show the full criteria

Inclusion criteria

* Definitive diagnosis of multiple sclerosis * Kurtzke Expanded Disability Status of 3.0 - 6.5 * Able to walk on a treadmill at a minimum of 0.5 miles per hour while holding onto handrails * Cognitively and emotionally competent * A Mini-Mental State Examination score > 21 * Composite score on the computerized Sensory Organization Test of \< 70

Exclusion criteria

* Documented MS-related relapse in the previous 6 months * Major MS-specific medication changes within the previous 3 months * Presence of another major co-morbidity such as neurological disorders, uncontrolled pain, hypertension, and diabetes

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Outcomes from the investigators' recent investigation suggested that a high dosage of challenging physical therapy exercises can result in clinically improvements in the postural balance and walking speed of individuals with MS. This investigation will evaluate mobility and postural balance improvements in individuals with MS who participate in a therapeutic protocol consisting of activity based exercises, and in individuals with MS that participate in challenging physical therapy protocol.

Papers

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History

    1. Started

      Oct 2014

    2. Main results due

      Jun 2015

    3. Finished

      Jun 2015

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