Attention/Working Memory Rehabilitation in Multiple Sclerosis: A Pilot Project Using Cogmed Working Memory Training

CompletedNot a drug-phase studyMS (type not specified)NCT02634567

What it found

No results found

We found no results in the registry or in papers.

This trial finished 8 years ago. We found no results in the registry or in any paper that cites it.

What was tested

Treatment tested

  • Cogmed Working Memory Training (CWMT)

What it measured

Main measures

  • Paced Auditory Serial Addition Test

    7 months

    Thinking and memory
  • Symbol Digit Modalities Test

    7 months

    Thinking and memory
  • Stroop colour word test

    7 months

    Thinking and memory

Other measures (19)

  • Judgement of Line Orientation

    7 months

    Thinking and memory
  • Controlled Oral Word Association Test

    7 months

    Thinking and memory
  • California Verbal Learning Test

    7 months

    Thinking and memory
  • Brief Visual Memory Test

    7 months

    Thinking and memory
  • Delis-Kaplan Executive Function System Sorting Test

    7 months

    Thinking and memory
  • Beck Depression Inventory - Fast Screen

    7 months

    Thinking and memoryMood and sleep
  • Hospital Anxiety and Depression Scale

    7 months

    Thinking and memoryMood and sleep
  • Fatigue Severity Scale

    7 months

    Thinking and memoryFatigue
  • Short Form Health Survey

    7 months

    Thinking and memory
  • Dysexecutive Questionnaire

    7 months

    Thinking and memory

Who could take part

MS (type not specified) · 18 to 64

Show the full criteria

Inclusion criteria

Gender Both: both female and male participants are being studied Age Limits Minimum Age: 18 years Maximum Age: 64 years Accepts Healthy Volunteers? No Eligibility Criteria Inclusion Criteria: * Males/Females, Ages 18-64, with any type of MS * Lower to moderate physical disability * Demonstrated impaired attention/working memory on 2 of 3 measures (Patients with a z-score lower than -1.5 on at least 2 of the 3 measures will be characterized as showing attention/working memory deficits) * Patients must have a Mac or personal computer (PC) computer at home with access to the internet

Exclusion criteria

* Clinical relapse/steroid treatment 1 month prior to study entry * Physical disability that prevents completion of study measures or training * History of severe mental illness or daily marijuana use * Those who do not meet the inclusion criteria.

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Patients diagnosed with any type of multiple sclerosis (MS) who show objective evidence of attention problems will be randomized to standard medical care (treatment as usual) or attention training, which will be completed at their home using a commercially available attention training task (Cogmed Working Memory Training - CWMT) for 5 weeks. Patients will undergo cognitive testing before and after intervention and at 6 months follow up.

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History

    1. Started

      Apr 2016

    2. Main results due

      Nov 2018

    3. Finished

      Dec 2018

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